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1. (WO2017096024) CYCLING THERAPY USING 3-(5-AMINO-2-METHYL-4-OXO-4H-QUINAZOLIN-3-YL)-PIPERIDINE-2,6-DIONE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/096024 International Application No.: PCT/US2016/064392
Publication Date: 08.06.2017 International Filing Date: 01.12.2016
IPC:
A61K 31/517 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
517
ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
CELGENE CORPORATION [US/US]; 86 Morris Avenue Summit, NJ 07901, US
Inventors:
HAGNER, Patrick; US
GANDHI, Anita; US
POURDEHNAD, Michael; US
Agent:
BHUMRALKAR, Megha; US
RIEGER, Dale, L.; US
GEORGE, Nikolaos, C.; US
INSOGNA, Anthony, M.; US
BRUNER, Michael, J.; US
Priority Data:
62/262,26302.12.2015US
Title (EN) CYCLING THERAPY USING 3-(5-AMINO-2-METHYL-4-OXO-4H-QUINAZOLIN-3-YL)-PIPERIDINE-2,6-DIONE
(FR) THÉRAPIE PRÉSENTANT DES CYCLES D'ADMINISTRATION DE 3-(5-AMINO-2-MÉTHYL-4-OXO-4H-QUINAZOLIN-3-YL)-PIPÉRIDINE-2,6-DIONE
Abstract:
(EN) Provided herein are methods of treating, preventing and/or managing cancer, including lymphoma, which comprise administering to a patient 3-(5-amino-2-methyl-4- oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof, or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or polymorph thereof in a cyclic therapy regimen.
(FR) L'invention concerne des méthodes de traitement, de prévention et/ou de prise en charge d'un cancer, qui consistent à administrer à un patient de la 3-(5-amino-2-méthyl-4-oxo-4H-quinazolin-3-yl)-pipéridine-2,6-dione, ou un énantiomère ou un mélange d'énantiomères de celle-ci, ou un sel, un solvate, un hydrate, un co-crystal, un clathrate ou un polymorphe pharmaceutiquement acceptable de celle-ci.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2016364753CA3006758SG11201804367PIL259597EP3383398KR1020180088401
MX2018006779BR112018010964EA201891289