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1. (WO2017096007) DEVICE AND METHOD FOR NERVE BLOCK BY LOCAL COOLING TO ROOM TEMPERATURE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/096007 International Application No.: PCT/US2016/064364
Publication Date: 08.06.2017 International Filing Date: 01.12.2016
IPC:
A61M 19/00 (2006.01) ,A61F 7/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
19
Devices for local anaesthesia; Devices for hypothermia
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
7
Heating or cooling appliances for medical or therapeutic treatment of the human body
Applicants:
UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION [US/US]; 1st Floor Gardner Steel Conference Center 130 Thackeray Avenue Pittsburgh, Pennsylvania 15260, US
Inventors:
TAI, Changfeng; US
Agent:
HIRSHMAN, Jesse, A.; US
JACKSON, Brian, J.; US
FORTNEY, Lester, N.; US
GUPTA, Meghana, B.; US
Priority Data:
62/262,44503.12.2015US
Title (EN) DEVICE AND METHOD FOR NERVE BLOCK BY LOCAL COOLING TO ROOM TEMPERATURE
(FR) DISPOSITIF ET MÉTHODE DE BLOCAGE DE NERF PAR REFROIDISSEMENT LOCAL JUSQU'À TEMPÉRATURE AMBIANTE
Abstract:
(EN) Provided herein are methods of nerve blockage, for example for treatment of obesity, heart failure, cardiovascular disease, muscle spasms, chronic pain, or urinary retention in a patient. The method comprises first heating a nerve above physiological temperature (e.g. 37°C in a human), such as from 43°C to 54°C for a duration that leads to reversible nerve blockage as opposed to nerve damage. Second, reversible nerve blockage is produced by cooling the nerve below physiological temperature to a temperature in which reversible nerve blockage is achieved, for example from 15°C to 30°C.
(FR) La présente invention concerne des méthodes de blocage de nerf, par exemple pour le traitement de l'obésité, d'une insuffisance cardiaque, d'une maladie cardio-vasculaire, de spasmes musculaires, d'une douleur chronique ou de la rétention urinaire chez un patient. La méthode consiste premièrement à chauffer un nerf à une température supérieure à la température physiologique (par exemple 37 °C chez l'homme), par exemple à une température de 43 °C à 54 °C pendant une durée qui conduit à un blocage réversible du nerf par opposition à une lésion nerveuse. Deuxièmement, un blocage réversible du nerf est produit par refroidissement du nerf d'une température inférieure à la température physiologique jusqu'à une température dans laquelle un blocage réversible du nerf est obtenu, par exemple à une température de 15 °C à 30 °C.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2016364743CA3006451IL259555CN108290023EP3383471US20180344518