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1. (WO2017095757) TOPICAL FORMULATIONS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/095757 International Application No.: PCT/US2016/063885
Publication Date: 08.06.2017 International Filing Date: 28.11.2016
IPC:
C07K 16/28 (2006.01) ,A01N 37/18 (2006.01) ,C07D 401/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
37
Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
18
containing the group -CO-N, e.g. carboxylic acid amides or imides; Thio-analogues thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
Applicants:
IGNYTA, INC. [US/US]; 4545 Town Centre Court San Diego, California 92121, US
Inventors:
PETERSON, Jeffrey Alan; US
SWEETANA, Stephanie Ann; US
Agent:
MORLEY, Marc T.; US
LEE-DUTRA, Alice; US
Priority Data:
62/261,20730.11.2015US
Title (EN) TOPICAL FORMULATIONS
(FR) FORMULATIONS TOPIQUES
Abstract:
(EN) Described herein are pharmaceutical formulations comprising 4-fluoro-N-methyl-N-(l-(4- (l-methyl-lH-pyrazol-5-yl)phthalazin-l-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide, or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical formulations are suitable for topical use, and methods of using such formulations in the treatment of subjects having cancer.
(FR) L'invention concerne des formulations pharmaceutiques comprenant du 4-fluoro-N-méthyl-N-(1-(4-(1-méthyl-1H-pyrazol-5-yl) phtalazine-1-yl)pipéridin-4-yl)-2-(trifluorométhyl)benzamide, ou un sel pharmaceutiquement acceptable de celui-ci, ces formulations pharmaceutiques conviennent pour une utilisation topique. L’invention concerne également des procédés d'utilisation de ces formulations dans le traitement de sujets atteints d'un cancer.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US20180256570CN108495862EP3383912