Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2017095487) MULTIPLEX CELLULAR REFERENCE MATERIALS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/095487 International Application No.: PCT/US2016/048668
Publication Date: 08.06.2017 International Filing Date: 25.08.2016
IPC:
C12Q 1/68 (2006.01) ,C12N 5/071 (2010.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
Applicants:
SERACARE LIFE SCIENCES, INC. [US/US]; 37 Birch Street Milford, MA 01757, US
Inventors:
HUANG, Catherine; US
ANEKELLA, Bharathi; US
NGUYEN, Lequan, T.; US
Agent:
BENNETT, Jonathan, D.; US
ABELLEIRA, Susan, A.; US
AKHIEZER, Alexander; US
BLOUNT, Jennifer, V.; US
GORDON, Dana, M.; US
Priority Data:
62/261,51401.12.2015US
62/323,65916.04.2016US
Title (EN) MULTIPLEX CELLULAR REFERENCE MATERIALS
(FR) MATÉRIELS DE RÉFÉRENCE CELLULAIRES MULTIPLEXÉS
Abstract:
(EN) Disclosed are nucleic acids, comprising a plurality of nucleotide sequences, and each nucleotide sequence of the plurality comprises a genotype that is associated with a disease or condition. For example, each nucleotide sequence of the plurality may be a human nucleotide sequence, and each genotype may be a somatic mutation that is associated with a neoplasm or a heart condition (e.g., cardiomyopathy). Also disclosed are cells comprising the nucleic acid, e.g., wherein the cell is a human cell. A related biological reference material comprises a plurality of cells comprising the nucleic acid, and a plurality of cells that do not comprise the nucleic acid (e.g., untransfected cells). The cells of the reference material may be fixed (e.g., with formalin) or embedded in paraffin.
(FR) L'invention concerne des acides nucléiques, comprenant une pluralité de séquences nucléotidiques, chaque séquence nucléotidique de la pluralité comprenant un génotype associé à une maladie ou à un état pathologique. Par exemple, chaque séquence nucléotidique de la pluralité peut être une séquence nucléotidique humaine, et chaque génotype peut être une mutation somatique qui est associée à un néoplasme ou un état cardiaque (par exemple, la cardiomyopathie). L'invention concerne également des cellules comprenant l'acide nucléique, par exemple, la cellule étant une cellule humaine. Un matériel biologique de référence associé comprend une pluralité de cellules comprenant l'acide nucléique, et une pluralité de cellules qui ne comprennent pas l'acide nucléique (par exemple des cellules non transfectées). Les cellules du matériel de référence peuvent être fixées (par exemple, avec du formol) ou incluses en paraffine.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2016362876CA3007056IL259448EP3384054US20190177794