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1. (WO2017095394) INTEGRATED SAMPLE PROCESSING SYSTEM
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/095394 International Application No.: PCT/US2015/063232
Publication Date: 08.06.2017 International Filing Date: 01.12.2015
IPC:
C12Q 1/68 (2006.01) ,C40B 60/12 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
C CHEMISTRY; METALLURGY
40
COMBINATORIAL TECHNOLOGY
B
COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
60
Apparatus specially adapted for use in combinatorial chemistry or with libraries
12
for screening libraries
Applicants:
AKONNI BIOSYSTEMS, INC. [US/US]; 400 Sagner Ave., Suite 300 Frederick, MD 21701, US
Inventors:
COONEY, Christopher, G.; US
HOLMBERG, Rebecca; US
BELGRADER, Phillip; US
QU, Peter, Qiang; US
Agent:
YE, Michael; Andrews Kurth, LLP 1350 I Street, N.W. Suite 1100 Washington, DC 20005, US
Priority Data:
Title (EN) INTEGRATED SAMPLE PROCESSING SYSTEM
(FR) SYSTÈME INTÉGRÉ DE TRAITEMENT D'ÉCHANTILLONS
Abstract:
(EN) An integrated sample purification system includes a housing, a sample container rack, a filter holder, and a cylindrical magnet. The sample container rack and the filter device holder are disposed in the housing. The sample container rack is configured to hold one or more sample containers, the filter device holder is configured to hold one or more filter devices. The cylindrical magnet is adjacent to and external to the sample container rack, and is rotated about a central, longitudinal axis of the magnet by an electric motor disposed in the housing to lyse cells. Molecules of interest in the lysed cells are purified using filters that bind specifically to the molecules of interest. The system is readily amenable to automation and rapid purification and analysis of molecules of interest, such as nucleic acids and proteins.
(FR) L'invention concerne un système intégré de purification d'échantillons comprenant un boîtier, une cassette à récipients d'échantillon, un support de filtre et un aimant cylindrique. La cassette à récipients d'échantillon et le support de filtre sont disposés dans le boîtier. La cassette à récipients d'échantillon est conçue pour contenir un ou plusieurs récipients d'échantillon, le support de filtre est conçu pour contenir un ou plusieurs dispositifs de filtre. L'aimant cylindrique est adjacent et externe à la cassette à récipients d'échantillon et tourne autour d'un axe central longitudinal de l'aimant par un moteur électrique disposé dans le boîtier pour lyser des cellules. Les molécules d'intérêt dans les cellules lysées sont purifiées au moyen de filtres qui lient spécifiquement les molécules d'intérêt. Le système est facilement prêt à l'automatisation et à la purification et à l'analyse rapides de molécules d'intérêt, telles que des acides nucléiques et des protéines.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA3007019IN201827022349EP3384042CN108603221