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1. (WO2017095132) AGONIST OF SPEXIN-BASED GALANIN TYPE 2 RECEPTOR AND USE THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/095132 International Application No.: PCT/KR2016/013950
Publication Date: 08.06.2017 International Filing Date: 30.11.2016
IPC:
A61K 38/10 (2006.01) ,A61K 9/00 (2006.01) ,C07K 7/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10
Peptides having 12 to 20 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
08
having 12 to 20 amino acids
Applicants:
주식회사 뉴라클사이언스 NEURACLE SCIENCE CO., LTD [KR/KR]; 서울시 성북구 안암로 145, 사학관 702-2호 702-2, Sanhakwan 145, Anam-ro, Seongbuk-gu, Seoul 02841, KR
Inventors:
성재영 SEONG, Jae Young; KR
황종익 HWANG, Jong-Ik; KR
김동훈 KIM, Dong-Hoon; KR
손기훈 SON, Gi Hoon; KR
이유나 LEE, Yoo-Na; KR
윤성식 YUN, Seongsik; KR
레예스알카라스아팍세데 REYES-ALCARAZ, Arfaxad; KR
Agent:
특허법인 충현 CHUNG HYUN PATENT & LAW FIRM; 서울시 서초구 동산로 23 베델회관 8층 Bethel Bldg. 8F., 23, Dongsan-ro Seocho-gu Seoul 06779, KR
Priority Data:
10-2015-016855530.11.2015KR
Title (EN) AGONIST OF SPEXIN-BASED GALANIN TYPE 2 RECEPTOR AND USE THEREOF
(FR) AGONISTE DU RÉCEPTEUR DE TYPE 2 DE LA GALANINE BASÉ SUR LA SPEXINE, ET UTILISATION DE CE DERNIER
(KO) 스펙신 기반 갈라닌 2형 수용체의 효현제 및 이의 용도
Abstract:
(EN) The present invention relates to an agonist of spexin-based galanin type 2 receptor and a use thereof. More specifically, the present invention provides a peptide-based agonist having improved specificity and stability to the galanin type 2 receptor, wherein the peptide-based agonist is involved in the regulation of physical functions in the body, such as feeding, anxiety, emotion, and addiction, in which the galanin type 2 receptor plays a role, thereby suppressing appetite, relieving anxiety disorders, and reducing the addiction to pleasure, and thus, the peptide-based agonist can be used to prevent or treat diseases induced by galanin type 2 receptor.
(FR) La présente invention concerne un agoniste du récepteur de type 2 de la galanine basé sur la spexine, et une utilisation de ce dernier. Plus particulièrement, la présente invention concerne un agoniste peptidique présentant une spécificité et stabilité améliorées vis-à-vis du récepteur de type 2 de la galanine, l'agoniste peptidique étant impliqué dans la régulation de fonctions physiologiques de l'organisme dans lesquelles le récepteur de type 2 de la galanine joue un rôle, telles que l'alimentation, l'anxiété, l'émotion et l'addiction, permettant de ce fait de supprimer l'appétit, de soulager des troubles anxieux, et de diminuer l'addiction au plaisir, et, en conséquence, l'agoniste peptidique peut être utilisé pour prévenir ou traiter des maladies induites par le récepteur de type 2 de la galanine.
(KO) 본 발명은 스펙신 기반 갈라닌 2형 수용체의 효현제 및 이의 용도에 관한 것으로, 보다 상세하게는, 본 발명은 갈라닌 수용체 2형에 대한 특이성과 안정성을 개선한 펩타이드계 효현제를 제공하며, 상기 펩타이드계 효현제는 갈라닌 수용체 2형이 담당하는 체내의 생리적 기능인 섭식, 불안, 감정, 중독 등의 조절에 관여하여 식욕을 억제하고 불안장애를 회복하며, 쾌락중독성을 감소시킬 수 있는 효과가 있어 갈라닌 2형 수용체에 의해 유도되는 질환의 예방 또는 치료에 사용할 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)
Also published as:
AU2016361783CA3003262CN108348570EP3384920US20180319841BR112018008315