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1. (WO2017093845) ANTIBODIES AND ANTIBODY FRAGMENTS FOR SITE-SPECIFIC CONJUGATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/093845 International Application No.: PCT/IB2016/057018
Publication Date: 08.06.2017 International Filing Date: 22.11.2016
IPC:
C07K 16/32 (2006.01) ,A61P 35/00 (2006.01) ,A61K 47/68 (2017.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
32
against translation products from oncogenes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
[IPC code unknown for A61K 47/68]
Applicants:
PFIZER INC. [US/US]; 235 East 42nd Street New York, New York 10017, US
Inventors:
MA, Dangshe; US
MARQUETTE, Kimberly Ann; US
GRAZIANI, Edmund Idris; US
SAPRA, Puja; US
TUMEY, Lawrence Nathan; US
PRASHAD, Nadira Anarkali; US
KHANDKE, Kiran Manohar; US
BENNETT, Eric M.; US
TCHISTIAKOVA, Lioudmila; US
Agent:
WALDRON, Roy F.; US
Priority Data:
62/260,85430.11.2015US
62/289,74401.02.2016US
62/409,32317.10.2016US
Title (EN) ANTIBODIES AND ANTIBODY FRAGMENTS FOR SITE-SPECIFIC CONJUGATION
(FR) ANTICORPS ET FRAGMENTS D'ANTICORPS POUR UNE CONJUGAISON SPÉCIFIQUE D'UN SITE
Abstract:
(EN) The inventionrelates to polypeptides, antibodies,and antigen-binding fragments thereof, that comprise a substitutedcysteine for site-specific conjugation.
(FR) L'invention concerne des polypeptides, des anticorps et leurs fragments de liaison à l'antigène, qui comprennent une cystéine substituée pour une conjugaison spécifique d'un site.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2016363374SG11201803679TMYPI 2018701998IL259643KR1020180083428ID2018/09272
IN201817016968EP3383919CN109071670BR112018010891PH1/2018/501042