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1. (WO2017093482) IMPROVED MEDIA FOR THE EXPRESSION OF RECOMBINANT VITAMIN K-DEPENDENT PROTEINS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/093482 International Application No.: PCT/EP2016/079585
Publication Date: 08.06.2017 International Filing Date: 02.12.2016
IPC:
C07K 14/745 (2006.01) ,C07K 5/02 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
745
Blood coagulation or fibrinolysis factors
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
02
containing at least one abnormal peptide link
Applicants:
CSL BEHRING RECOMBINANT FACILITY AG [CH/CH]; Wankdorfstrasse 10 3014 Bern, CH
Inventors:
LEE, Yih Yean; AU
LOW, Chee Kin Andrew; AU
AITKEN, Campbell Douglas; AU
BYRNE, Steven Patrick; AU
EDWARDS, Mark John Ferres; AU
Agent:
HAUSER, Hans-Peter; DE
BINSACK, Beate; DE
PETER, Beate; DE
LUDWIG, Holger; DE
Priority Data:
15197516.602.12.2015EP
Title (DE) IMPROVED MEDIA FOR THE EXPRESSION OF RECOMBINANT VITAMIN K-DEPENDENT PROTEINS
(EN) IMPROVED MEDIA FOR THE EXPRESSION OF RECOMBINANT VITAMIN K-DEPENDENT PROTEINS
(FR) MILIEUX AMÉLIORÉS POUR L'EXPRESSION DE PROTÉINES RECOMBINANTES VITAMINE K-DÉPENDANTES
Abstract:
(DE) The present invention relates to a method for increasing the activity and/or the yield of a recombinant vitamin K-dependent protein expressed in cell culture. The present invention further relates to uses and compositions of matter.
(EN) The present invention relates to a method for increasing the activity and/or the yield of a recombinant vitamin K-dependent protein expressed in cell culture. The present invention further relates to uses and compositions of matter.
(FR) La présente invention concerne un procédé pour augmenter l'activité et/ou le rendement d’une protéine recombinante vitamine K-dépendante exprimée en culture cellulaire. La présente invention concerne en outre des utilisations et des compositions de matière.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2016363789EP3383894US20180362952