Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2017093406) MULTISPECIFIC ANTIBODIES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/093406 International Application No.: PCT/EP2016/079435
Publication Date: 08.06.2017 International Filing Date: 01.12.2016
IPC:
C07K 16/00 (2006.01) ,C07K 16/14 (2006.01) ,C07K 16/46 (2006.01) ,C07K 14/39 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
14
against material from fungi, algae or lichens
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46
Hybrid immunoglobulins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
37
from fungi
39
from yeasts
Applicants:
UCB BIOPHARMA SPRL [BE/BE]; 60, Allée de la Recherche 1070 Brussels, BE
Inventors:
WRIGHT, Michael John; GB
Agent:
UCB INTELLECTUAL PROPERTY; c/o UCB Celltech 208 Bath Road Slough Berkshire SL1 3WE, GB
Priority Data:
1521393.703.12.2015GB
Title (EN) MULTISPECIFIC ANTIBODIES
(FR) ANTICORPS MULTISPÉCIFIQUES
Abstract:
(EN) The present invention relates to heterodimerically-tethered bispecific protein complexes (according to the general formula of A(A1)n-X:Y-B(B1)m and libraries/multiplexes thereof for use in research and therapy and in particular an in vitro/ex vivo method of detecting synergistic biological function of otherwise unknown pairs of targets. Such complexes may be used to capture soluble molecules secreted from a particular cell, in therapy, in research and for experimental purposes such as in assays to characterise patient populations by identifying cell populations relevant to a pathology or prognosis.
(FR) La présente invention concerne des complexes de protéines bispécifiques fixées hétérodimériquement (selon la formule générale A(A1)n-X:Y-B(B1)m et des banques/multiplexes de ces derniers pour une utilisation en recherche et en thérapie, et en particulier un procédé in vitro/ex vivo de détection d'une fonction biologique synergique de paires de cibles autrement inconnues. Ces complexes peuvent être utilisés pour capturer des molécules solubles sécrétées par une cellule particulière, en thérapie, en recherche et à des fins expérimentales par exemple, dans des dosages pour caractériser des populations de patients par l'identification des populations cellulaires correspondant à une pathologie ou un pronostic.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA3005496CN108473556IN201817018545EP3383899US20180334514BR112018010933
EA201891293