Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2017093147) METHOD FOR INACTIVATING XENOANTIGENS IN BIOLOGICAL TISSUES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/093147 International Application No.: PCT/EP2016/078898
Publication Date: 08.06.2017 International Filing Date: 25.11.2016
IPC:
A61L 27/36 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
36
containing ingredients of undetermined constitution or reaction products thereof
Applicants:
BIOCOMPATIBILITY INNOVATION SRL [IT/IT]; Via Enrico Petrella, 4 35132 Padova, IT
Inventors:
NASO, Filippo; IT
GANDAGLIA, Alessandro; IT
Agent:
RIGAMONTI, Dorotea; IT
Priority Data:
10201500007823630.11.2015IT
Title (EN) METHOD FOR INACTIVATING XENOANTIGENS IN BIOLOGICAL TISSUES
(FR) PROCÉDÉ D'INACTIVATION DE HÉTÉRO-ANTIGÈNES DANS DES TISSUS BIOLOGIQUES
Abstract:
(EN) A method for inactivating xenoantigens in biological tissues, particularly in tissues that can be used to manufacture bioprosthetic substitutes and/or in bioprosthetic substitutes that are already prepared and intended for human or veterinary clinical use. Such method entails the following steps: - providing a solution based on phenolic compounds, polyphenolic compounds or derivatives thereof, for the inactivation of at least part of the xenogeneic epitopes from such tissues; - incubating the samples to be treated in the various solutions based on phenols/polyphenols in controlled conditions; - subjecting the treated tissues to a series of washes.
(FR) L'invention concerne un procédé qui permet d'inactiver des hétéro-antigènes dans des tissus biologiques, en particulier dans des tissus qui peuvent être utilisés pour fabriquer des substituts bio-prothétiques et/ou dans des substituts bio-prothétiques qui sont déjà préparés et conçus pour une utilisation clinique, humaine ou vétérinaire. Un tel procédé consiste : - à fournir une solution à base de composés phénoliques, de composés polyphénoliques ou de dérivés de ceux-ci, pour l'inactivation d'au moins une partie des épitopes hétéro-géniques de tels tissus ; - à incuber les échantillons à traiter dans de diverses solutions à base de phénols/polyphénols dans des conditions contrôlées ; - à soumettre les tissus traités à une série de lavages.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA3006234AU2016363536IL259591CN108367098KR1020180090816EP3383446
IN201817021526CU2018000048ID2018/12130US20180353647BR112018011021