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1. (WO2017091895) PPAR-GAMMA ACTIVATORS AND THEIR THERAPEUTICAL USAGES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/091895 International Application No.: PCT/CA2016/051405
Publication Date: 08.06.2017 International Filing Date: 30.11.2016
Chapter 2 Demand Filed: 02.10.2017
IPC:
A61K 31/222 (2006.01) ,A61K 31/192 (2006.01) ,A61P 29/00 (2006.01) ,C07C 63/08 (2006.01) ,C07C 69/157 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
22
of acyclic acids, e.g. pravastatin
222
with compounds having aromatic groups, e.g. dipivefrine, ibopamine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
192
having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
63
Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings
04
Monocyclic monocarboxylic acids
06
Benzoic acid
08
Salts thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
69
Esters of carboxylic acids; Esters of carbonic or haloformic acids
02
Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
12
Acetic acid esters
14
of monohydroxylic compounds
145
of unsaturated alcohols
157
containing six-membered aromatic rings
Applicants:
THERIAC BIOMEDICALE INC. [CA/CA]; 346 av. Lethbridge Mont-Royal, Québec H3P 1E5, CA
Inventors:
ANTAKLY, Tony; CA
Agent:
BENOIT & COTE INC.; #300-560 East, Cremazie Blvd. Montréal, Québec H2P 1E8, CA
Priority Data:
62/261,62501.12.2015US
Title (EN) PPAR-GAMMA ACTIVATORS AND THEIR THERAPEUTICAL USAGES
(FR) ACTIVATEURS PPAR-GAMMA ET LEURS UTILISATIONS THÉRAPEUTIQUES
Abstract:
(EN) The invention relates to a composition for induction of activity of a nuclear receptor PPARy in a subject in need thereof, which comprises at least one of benzoate or a synergistic combination of benzoate and phenylacetate in association with a pharmaceutical carrier.
(FR) L'invention concerne une composition pour induire l'activité d'un récepteur nucléaire PPARy chez un sujet en ayant besoin, qui comprend au moins un benzoate ou une combinaison synergique de benzoate et de phénylacétate en association avec un excipient pharmaceutique.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA3007122AU2016363691EP3383384CN108697682US20190000790