Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2017091827) NOVEL ALPHA-HYDROXY CARBOXYLIC ACID AND DERIVATIVES AND OTHER GRAS BASED PRODRUGS OF OXYCODONE AND USES THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/091827 International Application No.: PCT/US2016/063834
Publication Date: 01.06.2017 International Filing Date: 28.11.2016
IPC:
A61K 31/485 (2006.01) ,A61P 25/36 (2006.01) ,C07D 489/02 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
485
Morphinan derivatives, e.g. morphine, codeine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
30
for treating abuse or dependence
36
Opioid-abuse
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
489
Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
02
with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
Applicants:
THOTTATHIL, John K. [US/US]; US
Inventors:
THOTTATHIL, John K.; US
Agent:
FUGIT, Donna R.; US
Priority Data:
14/953,39229.11.2015US
Title (EN) NOVEL ALPHA-HYDROXY CARBOXYLIC ACID AND DERIVATIVES AND OTHER GRAS BASED PRODRUGS OF OXYCODONE AND USES THEREOF
(FR) NOUVEL ACIDE ALPHA-HYDROXY CARBOXYLIQUE ET DÉRIVÉS ET AUTRES PROMÉDICAMENTS À BASE DE GRAS D’OXYCODONE ET LEURS UTILISATIONS
Abstract:
(EN) The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to the opioid oxycodone, in a manner that substantially decreases or deters the potential for opioid abuse, addiction, illicit and illegal use, and overdose. When delivered at the proper dosage, the pharmaceutical composition provides therapeutic activity similar to that of the parent active agent.
(FR) La présente invention concerne des composés et des compositions pharmaceutiques comprenant un ligand fixé à l’oxycodone opioïde, d’une manière qui réduit sensiblement ou empêche le potentiel d’abus, d’addiction, d’utilisation illicite et illégale, et d’overdose d’opioïdes. Lorsqu'elle est administrée sous une dose correcte, la composition pharmaceutique a un effet thérapeutique semblable à celui de l’agent actif parent.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3380098