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1. (WO2017091791) IDENTIFICATION OF BIOMARKERS IN SERUM SAMPLES COLLECTED FROM CLINICAL TRIALS BY MULTIPLEX TECHNOLOGY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/091791 International Application No.: PCT/US2016/063706
Publication Date: 01.06.2017 International Filing Date: 23.11.2016
Chapter 2 Demand Filed: 25.09.2017
IPC:
A61K 8/97 (2017.01) ,A61K 36/00 (2006.01) ,A61K 36/355 (2006.01) ,A61K 36/708 (2006.01) ,A61K 36/804 (2006.01) ,A61K 38/19 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
96
containing materials, or derivatives thereof, of undetermined constitution
97
of vegetable origin, e.g. plant extracts
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
35
Caprifoliaceae (Honeysuckle family)
355
Lonicera (honeysuckle)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
70
Polygonaceae (Buckwheat family), e.g. spineflower or dock
708
Rheum (rhubarb)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
80
Scrophulariaceae (Figwort family)
804
Rehmannia
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
Applicants:
SIRBAL LTD. [CY/CY]; 11, Agathonos Kapsalos Limassol 3087, CY
SHRAIBOM, Nadav [IL/CY]; CY
SINGH, Anu, T. [IN/IN]; IN
JAGGI, Manu [IN/IN]; IN
STEINBERG, Eran [US/US]; US
VERMA, Ritu [IN/IN]; IN
MADAAN, Alka [IN/IN]; IN
Inventors:
SHRAIBOM, Nadav; CY
SINGH, Anu, T.; IN
JAGGI, Manu; IN
STEINBERG, Eran; US
VERMA, Ritu; IN
MADAAN, Alka; IN
Agent:
SMITH, Andrew, V.; US
Priority Data:
62/259,05623.11.2015US
62/268,22616.12.2015US
62/355,61428.06.2016US
Title (EN) IDENTIFICATION OF BIOMARKERS IN SERUM SAMPLES COLLECTED FROM CLINICAL TRIALS BY MULTIPLEX TECHNOLOGY
(FR) IDENTIFICATION DE BIOMARQUEURS DANS DES ÉCHANTILLONS DE SÉRUM COLLECTÉS À PARTIR D'ESSAIS CLINIQUES PAR TECHNOLOGIE DE MULTIPLEXAGE
Abstract:
(EN) The present invention provides methods, compositions, and kits for the treatment and/or diagnosis of psoriasis. The invention includes a method for diagnosing psoriasis, comprising measuring a level or combination of levels of one or more of: IL-5, IL-6, IL-7, IL-10, IL-13, IL-33, FGF-B, GMCSF, VEGF, IL-33, MCP-1, or IP-10, or combinations thereof, in a sample from a patient; comparing said measured level or combination of levels; and correlating said level or combination of levels with a manifestation of psoriasis within said patient. A medicinal composition comprising an herbal combination of Da Huang, Sheng Di Huang, and Jin Yin Hua for the treatment of psoriasis in a patient. A kit for diagnosing and/or prognosing psoriasis in a patient.
(FR) La présente invention concerne des procédés, des compositions, et des trousses pour le traitement et/ou le diagnostic du psoriasis. L'invention comprend un procédé de diagnostic du psoriasis, comprenant la mesure d'un taux ou d'une combinaison de taux d'un ou plusieurs parmi : IL-5, IL-6, IL-7, IL-10, IL-13, IL-33, FGF-B, GMCSF, VEGF, IL-33, MCP-1, ou IP-10, ou des combinaisons de ceux-ci, dans un échantillon d'un patient; la comparaison dudit taux mesuré ou de ladite combinaison de taux; et la corrélation dudit taux ou de ladite combinaison de taux à une manifestation du psoriasis dans ledit patient. L'invention concerne en outre une composition médicinale comprenant une combinaison à base de plantes de Da Huang, Sheng Di Huang et Jin Yin Hua pour le traitement du psoriasis chez un patient. L'invention concerne en outre une trousse pour le diagnostic et/ou le pronostic du psoriasis chez un patient.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3380074US20180340943