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1. (WO2017091753) METHODS AND COMPOSITIONS FOR REDUCING VANCOMYCIN-RESISTANT ENTEROCOCCI INFECTION OR COLONIZATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/091753 International Application No.: PCT/US2016/063643
Publication Date: 01.06.2017 International Filing Date: 23.11.2016
IPC:
A01N 63/00 (2006.01) ,A01N 65/00 (2009.01) ,A61K 35/66 (2015.01) ,A61K 35/74 (2015.01) ,A61K 9/00 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
63
Biocides, pest repellants or attractants, or plant growth regulators containing micro-organisms, viruses, microbial fungi, animals, e.g. nematodes, or substances produced by, or obtained from micro-organisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
65
Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
74
Bacteria
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
Applicants:
MEMORIAL SLOAN-KETTERING CANCER CENTER [US/US]; 1275 York Avenue New York, NY 10065, US
Inventors:
PAMER, Eric; US
MCKENNEY, Peter; US
CABALLERO, Silvia; US
Agent:
LECOINTE, Michelle M.; US
LECOINTE, Michelle, M.; US
Priority Data:
62/260,16425.11.2015US
62/301,87301.03.2016US
Title (EN) METHODS AND COMPOSITIONS FOR REDUCING VANCOMYCIN-RESISTANT ENTEROCOCCI INFECTION OR COLONIZATION
(FR) PROCÉDÉS ET COMPOSITIONS POUR RÉDUIRE UNE INFECTION OU COLONISATION D'ENTEROCOCCI RÉSISTANT À LA VANCOMYCINE
Abstract:
(EN) The present invention relates to methods and compositions for reducing the risk and severity of vancomycin-resistant Enterococci (VRE) infection or colonization. The invention provides for a method for reducing the risk of VRE infection/colonization in a subject, comprising administering to a subject in need of such treatment a therapeutically effective amount of a composition comprising at least one of a Clostridium scindens and/or a Blautia producta in a formulation suitable for administration to the subject. The present invention also provides for a method of diagnosing a subject with a VRE infection/colonization, or at risk for VRE infection/colonization. The present invention also provides for a kit comprising the therapeutic composition described herein.
(FR) La présente invention concerne des procédés et des compositions pour réduire le risque et la gravité d'une infection ou colonisation d'Enterococci résistant à la vancomycine (VRE). L'invention concerne un procédé pour réduire le risque d'infection/colonisation de VRE chez un sujet, comprenant l'administration, à un sujet ayant besoin d'un tel traitement, d'une quantité thérapeutiquement efficace d'une composition comprenant Clostridium scindens et/ou Blautia producta dans une formulation appropriée pour l'administration au sujet. La présente invention concerne également un procédé de diagnostic d'un sujet ayant une infection/colonisation de VRE ou ayant un risque d'infection/colonisation de VRE. La présente invention concerne également un kit comprenant la composition thérapeutique de l'invention.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2016361583CA3006105EP3379935