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1. (WO2017091413) WATER EXTRACTS OF RHIZOMA COPTIDIS AND RADIX ASTRAGALI
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/091413 International Application No.: PCT/US2016/062292
Publication Date: 01.06.2017 International Filing Date: 16.11.2016
IPC:
A61K 33/24 (2006.01) ,A61K 36/48 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
48
Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
Applicants:
CHENG, Nanzheng [CN/US]; US
Inventors:
CHENG, Nanzheng; US
Agent:
KUNG, Viola T.; US
ARAIZA, Alberto; US
ASSEFA, Marcus; US
BECKER, Jordan M.; US
CHEN, Han-Wei (Harvey); US
COLEMAN, Brian R.; US
DICATO, Michael J.; US
FOWLER, Colin M.; US
GLENN, Michael A.; US
HENDRICKS, Donald M.; US
NAMA, Vinod; US
PETROVIC, Lena; US
PETTIT, Andrew T.; US
STUDULSKI, Steven M.; US
THOMAS, Julia A.; US
ZHANG, Yiming; US
Priority Data:
62/259,18024.11.2015US
Title (EN) WATER EXTRACTS OF RHIZOMA COPTIDIS AND RADIX ASTRAGALI
(FR) EXTRAITS AQUEUX DE RHIZOMA COPTIDIS ET DE RADIX ASTRAGALI
Abstract:
(EN) This invention relates to methods and compositions for providing improved insulin-sensitivity and/or enhanced insulin-like action, which leads to improved glucose uptake and utilization. The invention provides a method for increasing glucose uptake in a subject. The present invention also provides a method for regulating blood glucose level in a subject. The invention further provides a method for decreasing blood glucose level in a hyperglycemic subject. The methods comprise administering to a subject an effective amount of a water extract of Rhizome Coptidis and an effective amount of a water extract of Radix Astragali. A preferred weight ratio of Rhizome Coptidis to Radix Astragali is about 1:1.
(FR) La présente invention concerne des méthodes et des compositions permettant d'améliorer la sensibilité à l'insuline et/ou de stimuler une action analogue à l'insuline, ce qui conduit à une meilleure absorption et utilisation du glucose. L'invention concerne une méthode permettant d'accroître l'absorption du glucose chez un sujet. La présente invention concerne également une méthode permettant de réguler la glycémie chez un sujet ou d'abaisser la glycémie chez un sujet hyperglycémique. Les méthodes comprennent l'administration à un sujet d'une quantité efficace d'un extrait aqueux de Rhizome Coptidis et d'une quantité efficace d'un extrait aqueux de Radix Astragali. Un rapport en poids Rhizome Coptidis à Radix Astragali préféré est d'environ 1:1.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)