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1. (WO2017091017) COMPOSITION FOR INJECTION OF HYALURONIC ACID, CONTAINING HYALURONIC ACID DERIVATIVE AND DNA FRACTION, AND USE THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/091017 International Application No.: PCT/KR2016/013652
Publication Date: 01.06.2017 International Filing Date: 24.11.2016
IPC:
A61K 8/73 (2006.01) ,A61K 8/04 (2006.01) ,A61K 8/98 (2006.01) ,A61K 31/728 (2006.01) ,A61K 31/711 (2006.01) ,A61K 9/00 (2006.01) ,A61K 9/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
72
containing organic macromolecular compounds
73
Polysaccharides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
02
characterised by special physical form
04
Dispersions; Emulsions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
96
containing materials, or derivatives thereof, of undetermined constitution
98
of animal origin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
715
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
726
Glycosaminoglycans, i.e. mucopolysaccharides
728
Hyaluronic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7088
Compounds having three or more nucleosides or nucleotides
711
Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
06
Ointments; Bases therefor
Applicants:
(주)한국비엠아이 BMI KOREA CO., LTD [KR/KR]; 제주도 제주시 첨단로 7길 11 11 Cheomdan-ro 7-gil, Jeju-si, Jeju-do 63309, KR
Inventors:
김민경 KIM, Min-Kyoung; KR
우구 WOO, Koo; KR
백영준 BAIK, Yeong Jun; KR
이성희 LEE, Sung Hee; KR
민경우 MIN, Kyeong Woo; KR
Agent:
유미특허법인 YOU ME PATENT AND LAW FIRM; 서울시 강남구 테헤란로 115 115 Teheran-ro, Gangnam-gu, Seoul 06134, KR
Priority Data:
10-2015-016493224.11.2015KR
Title (EN) COMPOSITION FOR INJECTION OF HYALURONIC ACID, CONTAINING HYALURONIC ACID DERIVATIVE AND DNA FRACTION, AND USE THEREOF
(FR) COMPOSITION POUR L'INJECTION D'ACIDE HYALURONIQUE, CONTENANT UN DÉRIVÉ DE L'ACIDE HYALURONIQUE ET UNE FRACTION ADN, ET UTILISATION DE CETTE DERNIÈRE
(KO) 히알루론산 유도체 및 DNA 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용
Abstract:
(EN) The present invention relates to a composition for the injection of hyaluronic acid, in which a DNA fraction is contained in a cross-linked viscoelastic hyaluronic acid gel. More specifically, the present invention relates to a composition for the injection of hyaluronic acid, the composition containing a hyaluronic acid composition obtained by cross - linking hyaluronic acid under basicity at a degree of cross - linking of 0.1 - 200%, the hyaluronic acid composition being mixed with 0.1 - 50 wt% of the DNA fraction. The DNA fraction is selected from, for example, polynucleotides (PN) and polydeoxyribonucleotide (PDRN). The composition used for a cosmetic or therapeutic purpose has improved viscoelastic flow characteristics and enzyme resistance.
(FR) La présente invention concerne une composition pour l'injection d'acide hyaluronique, dans laquelle une fraction constituée d'ADN est contenue au sein d'un gel réticulé d'acide hyaluronique viscoélastique. Plus spécifiquement, la présente invention concerne une composition pour l'injection d'acide hyaluronique, la composition contenant une composition d'acide hyaluronique obtenu par réticulation d'acide hyaluronique sous conditions basiques avec un degré de réticulation compris entre 0,1 et 200 %, la composition d'acide hyaluronique étant mélangée avec 0,1 à 50 % en poids de la fraction ADN. La fraction ADN est sélectionné entre, par exemple, des polynucléotides (PN) et un polydésoxyribonucléotide (PDRN). La composition, utilisée dans un but thérapeutique ou cosmétique, présente de meilleures caractéristiques d'écoulement viscoélastique et de résistance aux enzymes.
(KO) 본 발명은 가교된 점탄성 히알루론산 겔에 DNA분획물이 포함된 히알루론산 주사용 조성물에 관한 것이다. 더욱 상세하게는 히알루론산을 염기성 하에서 가교도 0.1 % 내지 200 %사이에서 가교시킨 히알루론산 조성물을 포함하고, 이 조성물에 DNA분획물을 0.1 내지 50 중량% 혼합시킨 히알루론산 주사용 조성물에 관한 것이다. DNA분획물은 예를 들면, 폴리뉴클레오티드 (Polynucleotide, PN), 폴리데옥시리보뉴클레오티드 (Polydeoxyribonucleotide, PDRN)으로 부터 선택된다. 미용 목적 또는 치료적 목적으로 사용되는 상기 조성물은, 개선된 점탄성적 유동 특성 및 효소저항성을 갖는다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)
Also published as:
CN108289825EP3381438US20180325798