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1. (WO2017090721) METHOD OF DETERMINING QUANTITY OF OBJECTS TO BE DETECTED IN SPECIMEN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/090721 International Application No.: PCT/JP2016/084946
Publication Date: 01.06.2017 International Filing Date: 25.11.2016
IPC:
G01N 33/543 (2006.01) ,G01N 33/50 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Applicants:
オーソ・クリニカル・ダイアグノスティックス株式会社 ORTHO-CLINICAL DIAGNOSTICS KABUSHIKI KAISHA [JP/JP]; 東京都千代田区西神田3丁目5番2号 5-2, Nishikanda 3-chome, Chiyoda-ku, Tokyo 1010065, JP
古河電気工業株式会社 FURUKAWA ELECTRIC CO., LTD. [JP/JP]; 東京都千代田区丸の内2丁目2番3号 2-3, Marunouchi 2-chome, Chiyoda-ku, Tokyo 1008322, JP
Inventors:
杉田 悟 SUGITA, Satoru; JP
福嶋 將行 FUKUSHIMA, Masayuki; JP
西田 昌貴 NISHIDA, Masataka; JP
大久保 典雄 OHKUBO, Michio; JP
三好 一富 MIYOSHI, Kazutomi; JP
Agent:
正林 真之 SHOBAYASHI, Masayuki; JP
林 一好 HAYASHI, Kazuyoshi; JP
新山 雄一 NIIYAMA, Yuichi; JP
Priority Data:
2015-23078026.11.2015JP
Title (EN) METHOD OF DETERMINING QUANTITY OF OBJECTS TO BE DETECTED IN SPECIMEN
(FR) PROCÉDÉ DE DÉTERMINATION DE QUANTITÉ D'OBJETS À DÉTECTER DANS UN ÉCHANTILLON
(JA) 検体中の検出対象を定量する方法
Abstract:
(EN) Provided is a method by which the quantity of objects to be detected can be quickly determined with high sensitivity. The method of determining the quantity of objects to be detected in a specimen comprises: a mixing step for preparing a mixture by mixing the specimen and carrier particles that carry stimulus-responsive substances and a first affinity substance for the objects to be detected; a measurement step for placing the mixture under the condition that the stimulus-responsive substances aggregate, and measuring the particle diameter of a suspended solid in the mixture; and a determination step for determining, on the basis of the particle diameter, the quantity of the objects to be detected.
(FR) L'invention concerne un procédé par lequel la quantité d'objets à détecter peut être rapidement déterminée avec une sensibilité élevée. Le procédé de détermination de la quantité d'objets à détecter dans un échantillon comprend : une étape de mélange consistant à préparer un mélange par mélange de l'échantillon et de particules porteuses qui portent des substances répondant à un stimulus et une première substance d'affinité pour les objets à détecter ; une étape de mesure consistant à placer le mélange dans des conditions dans lesquelles les substances répondant à un stimulus s'agrègent, et à mesurer le diamètre de particule d'un solide en suspension dans le mélange ; et une étape de détermination consistant à déterminer, sur la base du diamètre de particule, la quantité des objets à détecter.
(JA) 検出対象を迅速にかつ高感度で定量することができる方法を提供すること。 検体中の検出対象を定量する方法は、刺激応答性物質及び検出対象に対する第1の親和性物質を担持する担体粒子と、検体とを混合し、混合物を調製する混合工程と、混合物を刺激応答性物質が凝集する条件下におき、混合物中の懸濁物の粒子径を測定する測定工程と、粒子径に基づき、検出対象の量を決定する決定工程と、を有する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
US20180348228