WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2017070676) NANOPARTICLES COMPRISING A METAL CORE SURROUNDED BY A MONOLAYER FOR LYMPH NODE TARGETING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/070676    International Application No.:    PCT/US2016/058482
Publication Date: 27.04.2017 International Filing Date: 24.10.2016
IPC:
A61K 9/00 (2006.01), A61K 38/00 (2006.01), A61K 9/51 (2006.01)
Applicants: MASSACHUSETTS INSTITTUE OF TECHNOLOGY [US/US]; 77 Massachusetts Avenue Cambridge, MA 20139 (US).
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE [CH/CH]; Route Cantonale 1015 Lausanne (CH)
Inventors: IRVINE, Darrell, J.; (US).
YANG, Yu-sang, Sabrina; (US).
BEKDEMIR, Ahmet; (CH).
STELLACCI, Francesco; (CH)
Agent: PABST, Patrea L.; (US).
SHYNTUM, Yvonne, Y.; (US).
VORNDRAN, Charles; (US).
MONHEIT, Rivka, D.; (US).
RAYMOND, Adam, S.; (US).
PABST, Patrea, L.; (US)
Priority Data:
62/245,845 23.10.2015 US
Title (EN) NANOPARTICLES COMPRISING A METAL CORE SURROUNDED BY A MONOLAYER FOR LYMPH NODE TARGETING
(FR) NANOPARTICULES COMPRENANT UN NOYAU MÉTALLIQUE ENTOURÉ D'UNE MONOCOUCHE POUR LE CIBLAGE DES GANGLIONS LYMPHATIQUES
Abstract: front page image
(EN)Amphiphilic gold nanoparticles (amph-NPs), composed of gold cores surrounded by an amphiphilic mixed organic ligand shell, are capable of embedding within and traversing lipid membranes. Active agent is bound thereto for use in vaccine and other adjuvant therapies, immunomodulation, and treatment of microbial infections, cancer, autoimmune disease, inflammation and inflammatory disorders.
(FR)La présente invention concerne des nanoparticules d'or amphiphiles (NP-amph), composées de noyaux d'or entourés d'une enveloppe de ligand organique mixte amphiphile, étant capables de s'incruster dans des membranes lipidiques et de les traverser. L'agent actif est lié à celles-ci pour une utilisation dans un vaccin et autres thérapies adjuvantes, une immunomodulation, et le traitement d'infections microbiennes, du cancer, de maladies auto-immunes, d'inflammations et de troubles inflammatoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)