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1. (WO2017070516) PROSTATE-TARGETING ADENO-ASSOCIATED VIRUS SEROTYPE VECTORS

Pub. No.:    WO/2017/070516    International Application No.:    PCT/US2016/058185
Publication Date: Fri Apr 28 01:59:59 CEST 2017 International Filing Date: Sat Oct 22 01:59:59 CEST 2016
IPC: A61K 38/17
A61K 48/00
A61P 35/00
C07K 14/005
C07K 14/075
C07K 14/47
C12N 15/63
C12N 5/10
C12N 15/861
Applicants: UNIVERSITY OF MASSACHUSETTS
Inventors: GAO, Guangping
AI, Jianzhong
LI, Hong
WEI, Qiang
Title: PROSTATE-TARGETING ADENO-ASSOCIATED VIRUS SEROTYPE VECTORS
Abstract:
The disclosure relates to compositions and methods for rAAV-mediated delivery of a transgene to a subject. In some embodiments, the rAAV transduces the prostate tissue of a subject. In some embodiments, the methods are useful for treatment of prostate disease (e.g., prostatitis, BPH, prostate cancer).