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1. (WO2017070464) COFACTOR ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER

Pub. No.:    WO/2017/070464    International Application No.:    PCT/US2016/058100
Publication Date: Fri Apr 28 01:59:59 CEST 2017 International Filing Date: Sat Oct 22 01:59:59 CEST 2016
IPC: A01N 43/04
A61K 31/70
C07H 19/00
Applicants: MEMORIAL SLOAN-KETTERING CANCER CENTER
Inventors: LUO, Minkui
CAI, Xiaochuan
WANG, Ke
LUX, Michaelyn
Title: COFACTOR ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER
Abstract:
Compounds having methyltransferase inhibitory activity are disclosed. The compounds have the structure (I) They are useful in the treatment of cancer and similar diseases associated with inappropriate methyltransferase activity.