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Machine translation
1. (WO2017070012) LAPACHONE DERIVATIVES CONTAINING TWO REDOX CENTERS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/070012    International Application No.:    PCT/US2016/056986
Publication Date: 27.04.2017 International Filing Date: 14.10.2016
IPC:
C07D 311/92 (2006.01), C07D 307/91 (2006.01)
Applicants: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM [US/US]; 201 West 7th Street Austin, TX 78701 (US).
UNIVERSIDADE FEDERAL DO CEARA; Avenida Da Universidade 2853-benfica 60020-181 Fortaleza, Ceara (BR).
UNIVERSIDADE FEDERAL DE MINAS GERAIS [BR/BR]; Avenida Antonio Carlos 6627-pampulha 31270-901 Belo Horizonte, Minas Gerais (BR).
UNIVERSIDADE FEDERAL DE SANTA CATARINA [BR/BR]; Campus Reitor Joao David Ferreira Lima S/n-trindade 88040-900 Florianopolis-sc (BR)
Inventors: BOOTHMAN, David, A.; (US).
DA SILVA JUNIOR, Eufranio, N.; (BR).
DA CRUZ, Eduardo, H.g.; (BR).
CAVALCANTI, Bruno, C.; (BR).
BRAGA, Antonio, L.; (BR).
PESSOA, Claudia; (BR).
SILVERS, Molly; (US)
Agent: LONG, S., Reid; (US)
Priority Data:
62/244,038 20.10.2015 US
Title (EN) LAPACHONE DERIVATIVES CONTAINING TWO REDOX CENTERS AND METHODS OF USE THEREOF
(FR) DÉRIVÉS DE LAPACHONE CONTENANT DEUX CENTRES REDOX ET PROCÉDÉS D'UTILISATION ASSOCIÉS
Abstract: front page image
(EN)Provided herein are compounds containing two redox centers including a chalcogen redox center of the formula: wherein: R1, R2, X1, X2, Y1, and m are as defined herein. Also provided herein are pharmaceutical composition of the present compounds and methods of treatment using the compounds including their use in the treatment of cancer.
(FR)La présente invention concerne des composés contenant deux centres redox comprenant un centre redox chalcogène de formule : dans laquelle : R1, R2, X1, X2, Y1 et m sont tels que définis dans la description. L'invention concerne également des compositions pharmaceutiques des présents composés et des procédés de traitement utilisant les composés, notamment leur utilisation dans le traitement du cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)