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1. (WO2017068388) USE OF SYNTHETIC PNTX-19 PEPTIDE FOR THE TREATMENT OF PAIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/068388    International Application No.:    PCT/IB2015/057220
Publication Date: 27.04.2017 International Filing Date: 18.09.2015
IPC:
C07K 7/08 (2006.01), A61K 38/10 (2006.01), A61P 25/04 (2006.01)
Applicants: UNIVERSIDADE FEDERAL DE MINAS GERAIS - UFMG [BR/BR]; Avenida Antônio Carlos, 6627, Unidade Administrativa II, 2° andar, sala 2012. Pampuha. 31270-901 Belo Horizonte (BR).
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE MINAS GERAIS- FAPEMIG [BR/BR]; Rua Raul Pompéia, 101, 11° andar, Bairro São Pedro 30330-080 Belo Horizonte (BR)
Inventors: DIMITRI GAMA DUARTE, Igor; (BR).
DE LIMA PEREZ GARCIA, Maria Elena; (BR).
NOGUEIRA FREITAS, Ana Cristina; (BR).
DA FONSECA PACHECO, Daniela; (BR)
Agent: DE CASTRO LEITE GORI, Ana Luiza; (BR)
Priority Data:
Title (EN) USE OF SYNTHETIC PNTX-19 PEPTIDE FOR THE TREATMENT OF PAIN
(FR) UTILISATION DU PEPTIDE SYNTHÉTIQUE PNTX-19 POUR LE TRAITEMENT DE LA DOULEUR
(PT) USO DO PEPTIDEO SINTETICO PNTX-19 PARA TRATAMENTO DE DOR
Abstract: front page image
(EN)The present invention relates to the use of the synthetic PnTx-19 peptide for preparing analgesic medicinal drugs for the treatment of patients suffering from neuropathic pain, nociceptive pain (sensitisation of nociceptors by prostaglandin E2) and inflammatory pain. The synthetic PnTx-19 peptide is a very interesting pharmacological tool for use as an analgesic medicinal drug, since it triggers an antinociceptive response via cannabinoid and opioid and probably does not develop drug tolerance or dependence.
(FR)La présente invention concerne l'utilisation du peptide synthétique PnTx-19 dans la préparation de médicaments analgésiques pour le traitement de patients souffrant de douleur neuropathique, de douleur nociceptive (sensibilisation de nocicepteurs par prostaglandine E2) et de douleur inflammatoire. Le peptide synthétique PnTx-19 est un outil pharmacologique très intéressant pour une utilisation comme médicament analgésique étant donné qu'il déclenche une réponse antinociceptive via cannabinoïde et opioïde et ne provoque probablement pas de tolérance ni de dépendance.
(PT)A presente invenção refere-se uso do peptídeo sintético PnTx-19 na preparação de medicamentos analgésicospara o tratamento de pacientesportadores de dor neuropática, dor nociceptiva (sensibilização de nociceptores por prostaglandina E2) e inflamatória. O peptídeo sintético PnTx-19 é uma ferramenta farmacológica bastante interessante para o uso como medicamento analgésico uma vez que desencadeia resposta antinociceptiva via canabinoide e opioide e provavelmente não desencadeia tolerância nem dependência.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Portuguese (PT)
Filing Language: Portuguese (PT)