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1. (WO2017068359) METHOD FOR DETECTING NUCLEOSOMES CONTAINING HISTONE MODIFICATIONS AND VARIANTS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/068359 International Application No.: PCT/GB2016/053288
Publication Date: 27.04.2017 International Filing Date: 21.10.2016
IPC:
G01N 33/574 (2006.01) ,G01N 33/68 (2006.01)
Applicants: BELGIAN VOLITION SPRL[BE/BE]; 22 Rue Phocas Lejeune BE-5032 Isnes, BE
Inventors: MICALLEF, Jacob Vincent; BE
ECCLESTON, Mark, Edward; BE
Agent: AITKEN, Elizabeth; GB
GIBSON, Mark; GB
Priority Data:
1518674.521.10.2015GB
Title (EN) METHOD FOR DETECTING NUCLEOSOMES CONTAINING HISTONE MODIFICATIONS AND VARIANTS
(FR) PROCÉDÉ DE DÉTECTION DE NUCLÉOSOMES CONTENANT DES MODIFICATIONS ET VARIANTS D'HISTONE
Abstract:
(EN) The present invention relates to a method for detecting and measuring the presence of cell free mono-nucleosomes and oligo-nucleosomes that contain histone H1or a histone H1 modification, variant or isoform,and the use of such measurements for the detection and diagnosis of disease.
(FR) Cette invention concerne un procédé permettant de détecter et de mesurer la présence de mono-nucléosomes et d'oligo-nucléosomes acellulaires qui contiennent une histone H1 or une modification, un variant ou une isoforme d'histone H1, et l'utilisation de ces mesures pour dépister et diagnostiquer une maladie.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)