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1. (WO2017068352) METHODS
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Pub. No.: WO/2017/068352 International Application No.: PCT/GB2016/053278
Publication Date: 27.04.2017 International Filing Date: 20.10.2016
IPC:
A61K 39/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
Applicants:
THE ROYAL VETERINARY COLLEGE [GB/GB]; University of London The Camden Campus Royal College Street London NW1 0TU, GB
Inventors:
WERLING, Dirk; GB
Agent:
PILKINGTON, Stephanie Joan; GB
Priority Data:
1518762.822.10.2015GB
Title (EN) METHODS
(FR) PROCÉDÉS
Abstract:
(EN) A preparation of an inactivated or freeze-dried yeast cell (or cell-surface-containing portion thereof) expressing a porcine viral epitope, wherein the epitope is expressed on the surface of the yeast cell. The yeast is typically is non-viable. The yeast is typically from the genus Saccharomyces, and is preferably Saccharomyces cerevisiae, but may be from the genus Pichia, for example Pichia pastoris, or may be from the genus Kluyveromyces, for example K. lactis. The viral epitope may be from a Coronavirus, optionally from PEDV, TGEV, porcine hemagglutinating encephalomyelitis virus or PRCV; a porcine Rotavirus; or a virus of the Circoviridae family, optionally from PCV2.
(FR) La présente invention concerne une préparation d'une cellule de levure inactivée ou lyophilisée (ou d'une partie de celle-ci contenant la surface cellulaire) exprimant un épitope viral porcin, l'épitope étant exprimé sur la surface de la cellule de levure. La levure n'est typiquement pas viable. La levure est typiquement du genre Saccharomyces, et de préférence Saccharomyces cerevisiae, mais peut être du genre Pichia, par exemple, Pichia pastoris, ou peut être du genre Kluyveromyces, par exemple K. lactis. L'épitope viral peut provenir d'un Coronavirus, éventuellement du PEDV, du TGEV, du virus de l'encéphalomyélite hémagglutinante porcine ou du PRCV; d'un rotavirus porcin, ou d'un virus de la famille Circoviridae, facultativement du PCV2.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)