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1. (WO2017068351) SOLID FORMULATION

Pub. No.:    WO/2017/068351    International Application No.:    PCT/GB2016/053276
Publication Date: Fri Apr 28 01:59:59 CEST 2017 International Filing Date: Fri Oct 21 01:59:59 CEST 2016
IPC: A61K 9/00
A61K 9/20
A61K 38/26
A61K 38/29
A61K 38/31
A61P 3/10
A61P 5/18
A61P 35/00
Applicants: ENESI PHARMA LIMITED
Inventors: TIAN, Wei
ZAJICEK, Richard
Title: SOLID FORMULATION
Abstract:
A solid dosage form for injection and a method of making said dosage form wherein the dosage form has a moisture content of 5% (w/w) or less. The solid dosage form comprises a dried matrix including a first excipient and 0.01 to 50 % (w/w) or more than50% and up to80%(w/w) of a therapeutic peptide; and one or more additional excipients and at least 5 % (w/w) of CMC, based on the total weight of the solid dosage form, wherein the dosage form has a width of 0.5mm to 2mm.