Search International and National Patent Collections

1. (WO2017068064) PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS

Pub. No.:    WO/2017/068064    International Application No.:    PCT/EP2016/075269
Publication Date: Fri Apr 28 01:59:59 CEST 2017 International Filing Date: Fri Oct 21 01:59:59 CEST 2016
IPC: C07D 405/14
C07D 401/04
C07D 409/14
C07D 417/14
C07D 471/04
A61K 31/4427
A61P 29/00
Applicants: SELVITA S.A.
Inventors: RZYMSKI, Tomasz
MILIK, Mariusz
BRZOZKA, Krzysztof
FABRITIUS, Charles-Henry
KUCWAJ-BRYSZ, Katarzyna
KULESZA, Urszula
WINCZA, Ewelina
DREAS, Agnieszka
GALEZOWSKI, Michal
Title: PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS
Abstract:
Disclosed in the present application is a compound of formula (I) as defined herein as well as a pharmaceutical composition comprising said compound. Further disclosed in the present application is the use of such pharmaceutical compositions for treating diseases, namely inter alia for use in the treatment of cancer, metabolic, inflammatory, autoimmune and viral diseases. The compounds disclosed herein are inhibitors of MNK1 and/or MNK2 kinases.