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1. (WO2017066714) ANTI-VSIG1 ANTIBODIES AND DRUG CONJUGATES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/066714 International Application No.: PCT/US2016/057231
Publication Date: 20.04.2017 International Filing Date: 14.10.2016
IPC:
C07K 16/28 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
COMPUGEN LTD. [IL/IL]; 26 Harokmim Street 5885849 Holon, IL
DRAKE, Andrew, W. [US/US]; IL
Inventors:
DRAKE, Andrew, W.; IL
POW, Andrew; IL
HANSEN, Kyle; IL
BENITA, Yair; IL
COJOCARU, Gad, S.; IL
SAMEAH-GREENWALD, Shirley; IL
Agent:
MACDOUGALL, Christina, A.; US
ANTCZAK, Andrew; US
MANN, Jeffry, S.; US
SILVA, Robin; US
TALUKDER, Gargi; US
Priority Data:
62/242,90816.10.2015US
62/247,41428.10.2015US
Title (EN) ANTI-VSIG1 ANTIBODIES AND DRUG CONJUGATES
(FR) CONJUGUÉS D'ANTICORPS ANTI-VSIG1 ET DE MÉDICAMENTS
Abstract:
(EN) The disclosure relates generally to compounds with anti-cancer activity and more specifically to antibodies conjugated with chemotherapeutic drugs or toxins. The disclosure also relates to methods of using antibody-drug conjugate compounds for in vitro, in situ, and in vivo diagnosis or treatment of specific cancers.
(FR) L'invention concerne de manière générale des composés ayant une activité anticancéreuse et plus spécifiquement des anticorps conjugués avec des médicaments chimiothérapeutiques ou des toxines. L'invention concerne également des méthodes d'utilisation de composés de conjugués de médicaments-anticorps pour le diagnostic ou le traitement in vitro, in situ, et in vivo de cancers spécifiques.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)