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1. (WO2017066611) COMBINATION THERAPY FOR TREATING MALIGNANCIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/066611    International Application No.:    PCT/US2016/057102
Publication Date: 20.04.2017 International Filing Date: 14.10.2016
IPC:
A61K 31/53 (2006.01), A61K 31/7068 (2006.01), A61K 45/06 (2006.01), A61P 35/02 (2006.01), A61P 35/00 (2006.01)
Applicants: CELGENE CORPORATION [US/US]; 86 Morris Avenue Summit, NJ 07901 (US).
AGIOS PHARMACEUTICALS, INC. [US/US]; 88 Sidney Street Cambridge, MA 02139 (US)
Inventors: CHOPRA, Vivek, Saroj, Kumar; (US).
DIMARTINO, Jorge; (US).
KENVIN, Laurie, A.; (US).
KNIGHT, Robert, Douglas; (US).
MACBETH, Kyle; (US).
VISWANADHAN, Krishnan; (US).
XU, Qiang; (US).
AGRESTA, Samuel, V.; (US)
Agent: RIEGER, Dale, L.; (US).
BRUNER, Michael, J.; (US).
INSOGNA, Anthony, M.; (US).
GEORGE, Nikolaos, C.; (US)
Priority Data:
62/242,218 15.10.2015 US
Title (EN) COMBINATION THERAPY FOR TREATING MALIGNANCIES
(FR) POLYTHÉRAPIE POUR LE TRAITEMENT DE MALIGNITÉS
Abstract: front page image
(EN)Provided are methods and compositions for treating cancers in patients carrying an IDH2 mutation using a combination of an inhibitor of a mutant IDH2 enzyme and a DNA demethylating agent.
(FR)L'invention concerne des méthodes et des compositions pour le traitement de cancers chez des patients porteurs d'une mutation IDH2 à l'aide d'une combinaison d'un inhibiteur d'une enzyme IDH2 mutante et d'un agent de déméthylation de l'ADN.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)