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1. (WO2017066459) INHIBITION OF NEDDYLATION USING GLYCYL-tRNA SYNTHETASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/066459    International Application No.:    PCT/US2016/056862
Publication Date: 20.04.2017 International Filing Date: 13.10.2016
IPC:
A61K 38/53 (2006.01), A61P 35/00 (2006.01), C07H 21/02 (2006.01), C07K 16/40 (2006.01), C12N 5/04 (2006.01), C12N 5/07 (2010.01), C12Q 1/48 (2006.01)
Applicants: THE SCRIPPS RESEARCH INSTITUTE [US/US]; 10550 North Torrey Pine Road La Jolla, CA 92037 (US)
Inventors: YANG, Xiang-Lei; (US).
MO, Zhongying; (US).
SCHIMMEL, Paul; (US)
Agent: MALLON, Joseph, J.; (US)
Priority Data:
62/241,386 14.10.2015 US
Title (EN) INHIBITION OF NEDDYLATION USING GLYCYL-tRNA SYNTHETASE INHIBITORS
(FR) INHIBITION DE NEDDYLATION À L’AIDE D’INHIBITEURS DE GLYCYL-ARNT SYNTHÉTASE
Abstract: front page image
(EN)Disclosed herein are methods and compositions for inhibiting neddylation using Glycyl-tRNA synthase (GlyRS) inhibitors. Also disclosed are related compositions and methods for treating diseases such as cancer.
(FR)L'invention concerne des méthodes et des compositions pour inhiber la neddylation à l'aide d’inhibiteurs de glycyl-ARNt synthase (GlyRS). L'invention concerne également des compositions et des méthodes associées pour le traitement de maladies telles que le cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)