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1. (WO2017066402) 2,4-DIHYDROXY-NICOTINAMIDES AS APJ AGONISTS

Pub. No.:    WO/2017/066402    International Application No.:    PCT/US2016/056769
Publication Date: Fri Apr 21 01:59:59 CEST 2017 International Filing Date: Fri Oct 14 01:59:59 CEST 2016
IPC: C07D 401/14
C07D 405/14
C07D 413/14
C07D 213/82
C07D 401/06
C07D 401/12
C07D 413/12
C07D 417/12
C07D 417/14
C07D 471/10
C07D 491/107
C07D 498/10
A61K 31/4427
A61P 9/00
Applicants: BRISTOL-MYERS SQUIBB COMPANY
Inventors: KIM, Soong-Hoon
CHAO, Hannguang J.
FINLAY, Heather
JIANG, Ji
JOHNSON, James A.
LAWRENCE, R. Michael
MYERS, Michael C.
PHILLIPS, Monique
TORA, George O.
MENG, Wei
Title: 2,4-DIHYDROXY-NICOTINAMIDES AS APJ AGONISTS
Abstract:
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.