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Machine translation
1. (WO2017066227) COMPOUNDS USEFUL AS IMMUNOMODULATORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/066227    International Application No.:    PCT/US2016/056504
Publication Date: 20.04.2017 International Filing Date: 12.10.2016
IPC:
C07D 403/12 (2006.01), C07D 401/14 (2006.01), C07D 213/71 (2006.01), C07D 213/85 (2006.01), C07D 401/12 (2006.01), C07D 455/02 (2006.01), C07D 207/12 (2006.01), A61K 31/4427 (2006.01), A61P 35/00 (2006.01), A61P 37/00 (2006.01)
Applicants: BRISTOL-MYERS SQUIBB COMPANY [US/US]; Route 206 and Province Line Road Princeton, New Jersey 08543 (US)
Inventors: YEUNG, Kap-Sun; (US).
CONNOLLY, Timothy P.; (US).
FRENNESSON, David B.; (US).
GRANT-YOUNG, Katharine A.; (US).
HEWAWASAM, Piyasena; (US).
LANGLEY, David R.; (US).
MENG, Zhaoxing; (US).
MULL, Eric; (US).
PARCELLA, Kyle E.; (US).
SAULNIER, Mark George; (US).
SUN, Li-Qiang; (US).
WANG, Alan Xiangdong; (US).
XU, Ningning; (US).
ZHU, Juliang; (US).
SCOLA, Paul Michael; (US)
Agent: MINGO, Pamela A.; (US).
BELLOMY, Gregory R.; (US).
CHAO, Yuan; (US).
CLAUSS, Isabelle M.; (US).
D'AMICO, Stephen C.; (US).
DELAUNEY, Ashton J.; (US).
EPPERSON, James; (US).
FARQUHARSON-TORRES, Serena; (US).
FRANK, Eve; (US).
GOLIAN, Paul D.; (US).
GREENBLATT, Gary D.; (US).
GUO, Z. Angela; (US).
HADAD, Henry; (US).
HAI, Bing; (US).
JACOBSEN, Barry H.; (US).
KORSEN, Elliott; (US).
LIU, Hong; (US).
LU, Yong; (US).
PARLET, Nickki L.; (US).
SUN, Jing G.; (US).
VANATTEN, Mary K.; (US).
VOLLES, Warren K.; (US).
WALSH, Brian J.; (US)
Priority Data:
62/242,072 15.10.2015 US
15/290,167 11.10.2016 US
Title (EN) COMPOUNDS USEFUL AS IMMUNOMODULATORS
(FR) COMPOSÉS UTILES EN TANT QU'IMMUNOMODULATEURS
Abstract: front page image
(EN)The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases. The compounds have formula (I), wherein R2 is selected from (II) and (III).
(FR)La présente invention concerne de manière générale des composés utiles en tant qu'immunomodulateurs. Cette invention concerne des composés, des compositions comprenant ces composés, et leurs procédés d'utilisation. L'invention concerne en outre des compositions pharmaceutiques comprenant au moins un composé selon l'invention, qui sont utiles pour le traitement de différentes maladies, y compris du cancer et de maladies infectieuses. Les composés ont la formule suivante (I) : dans laquelle R2 est sélectionné parmi (II) : et (III) :
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)