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1. (WO2017066070) ACETATE COMPLEXES AND METHODS FOR ACETATE QUANTIFICATION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/066070 International Application No.: PCT/US2016/055673
Publication Date: 20.04.2017 International Filing Date: 06.10.2016
IPC:
C07F 15/02 (2006.01) ,A61K 49/06 (2006.01)
Applicants: GENERAL ELECTRIC COMPANY[US/US]; One River Road Schenectady, New York 12345, US
Inventors: LEACH, Andrew; US
CHEN, Rui; US
PALACIOS, Manuel; US
Agent: BAXTER, William; US
DIVINE, Lucas; US
DEVINS, Elizabeth; US
GROETHE, Jacob; US
VIVENZIO, Marc; US
RICAMATO, Anthony; US
Priority Data:
14/884,99216.10.2015US
Title (EN) ACETATE COMPLEXES AND METHODS FOR ACETATE QUANTIFICATION
(FR) COMPLEXES D'ACÉTATE ET PROCÉDÉS DE QUANTIFICATION D'ACÉTATE
Abstract: front page image
(EN) The present invention is directed to methods of acetate quantification and acetate complexes useful in the methods of acetate quantification. Such methods and complexes are useful for any application where acetate quantification is desired, including measuring of concentration of 13C hyperpolarized acetate for imaging agent quality control in MRI and NMR spectroscopy. The disclosed acetate complexes may be prepared from acetate, Fe3+, and sulfosalicylic acid and from acetate, Fe3+, and salicylic acid.
(FR) La présente invention concerne des procédés de quantification d'acétate et des complexes d'acétate utiles dans les procédés de quantification d'acétate. De tels procédés et complexes sont utiles pour toute application dans laquelle la quantification d'acétate est souhaitée, comprenant la mesure de la concentration en 13C-acétate hyperpolarisé pour l'imagerie de contrôle de la qualité d'un agent en IRM et spectroscopie RMN. Lesdits complexes d'acétate de la présente invention peuvent être préparés à partir d'acétate, de Fe3+, et d'acide sulfosalicylique et d'acétate, de Fe3+, et d'acide salicylique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)