An instrument handle and replaceable tip may include a reusable instrument handle and a single-use instrument tip. The instrument tip may include an outer base, a nosecone, a pressure mechanism, a hypodermic tube, a blank, and a fixation mechanism. The instrument handle may include an actuation structure, a fixation mechanism receptacle, and an instrument tip housing. The fixation mechanism and the fixation mechanism receptacle may be configured to temporarily fix the instrument tip in the instrument tip housing. A compression of the actuation structure may be configured to actuate the hypodermic tube relative to the blank. The instrument tip may be removed from the instrument tip housing after use by removing the fixation mechanism from the fixation mechanism receptacle.