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1. (WO2017064628) C-3 NOVEL TRITERPENONE WITH C-28 UREA DERIVATIVES AS HIV INHIBITORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/064628 International Application No.: PCT/IB2016/056099
Publication Date: 20.04.2017 International Filing Date: 12.10.2016
IPC:
A61K 31/00 (2006.01) ,A61K 31/58 (2006.01) ,C07J 63/00 (2006.01)
Applicants: HETERO LABS LIMITED[IN/IN]; Plot No B-80 & 81 A.P.I.E, Balanagar Hyderabad, 500018, IN
Inventors: BANDI, Parthasaradhi Reddy; IN
KURA, Rathnakar Reddy; IN
GAZULA LEVI, David Krupadanam; IN
ADULLA, Panduranga Reddy; IN
KASIREDDY, Bhaskar Reddy; IN
WILD, Carl Thomas; US
MARTIN, David Eugene; US
NITZ, Theodore John; US
Priority Data:
5467/CHE/201513.10.2015IN
Title (EN) C-3 NOVEL TRITERPENONE WITH C-28 UREA DERIVATIVES AS HIV INHIBITORS
(FR) NOUVELLE TRITERPÉNONE EN C-3 AVEC DES DÉRIVÉS D'URÉE EN C-28 EN TANT QU'INHIBITEURS DE VIH
Abstract: front page image
(EN) The present invention relates to C-3 novel triterpenone with C-28 urea derivatives of formula (I); or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable hydrates, tautomers, stereoisomers, prodrugs, compositions or combination thereof, wherein R1, R2, R3, W, J and X are as defined herein. The present invention also relates to pharmaceutical compositions comprising compounds of formula (I) useful for the treatment of viral diseases and particularly HIV mediated diseases.
(FR) La présente invention concerne une nouvelle triterpénone en C-3 avec des dérivés d'urée en C-28 de formule (I); ou des sels pharmaceutiquement acceptables, des solvates pharmaceutiquement acceptables, des hydrates pharmaceutiquement acceptables, des tautomères, des stéréo-isomères, des promédicaments, des compositions ou une combinaison de ceux-ci, dans laquelle R1, R2, R3, W, J et X ont la signification indiquée dans la description. La présente invention concerne également des compositions pharmaceutiques comprenant des composés de formule (I) utiles pour le traitement de maladies virales et en particulier de maladies médiées par le VIH.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)