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1. (WO2017064571) VACCINATION WITH IMMUNO-ISOLATED CELLS PRODUCING AN IMMUNOMODULATOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/064571    International Application No.:    PCT/IB2016/001968
Publication Date: 20.04.2017 International Filing Date: 26.09.2016
IPC:
A61K 39/00 (2006.01), A61K 39/39 (2006.01)
Applicants: MAXIVAX SA [CH/CH]; Rue de l'Athenee 24 Geneve (CH)
Inventors: MACH, Nicolas; (CH)
Agent: MOORE, Jacqueline Frances; Cooley (UK) LLP Dashwood 69 Old Broad Street London EC2M 1QS (GB)
Priority Data:
62/232,940 25.09.2015 US
62/384,416 07.09.2016 US
Title (EN) VACCINATION WITH IMMUNO-ISOLATED CELLS PRODUCING AN IMMUNOMODULATOR
(FR) VACCINATION AVEC DES CELLULES IMMUNO-ISOLÉES PRODUISANT UN IMMUNOMODULATEUR
Abstract: front page image
(EN)Provided herein are vaccine compositions containing at least one retrievable biocompatible macrocapsule containing immuno-isolated allogeneic cells that secrete an immunomodulator such as GM-CSF (granulocyte-macrophage colony stimulating factor) and an antigenic component such as autologous tumor cells or infectious agents. Also provided are kits and pharmaceutical compositions containing the vaccine compositions as well as said products for use in methods for therapeutic or preventive vaccination against tumors or infectious agents.
(FR)L'invention concerne des compositions vaccinales contenant au moins une macrocapsule biocompatible récupérable contenant des cellules allogéniques immuno-isolées qui sécrètent un immunomodulateur tel que GM-CSF (facteur stimulant les colonies de granulocytes et de macrophages) et un composant antigénique telles que des cellules tumorales autologues ou des agents infectieux. L'invention concerne également des kits et des compositions pharmaceutiques contenant les compositions vaccinales, ainsi que des procédés d'utilisation de celles-ci pour la vaccination thérapeutique ou préventive contre des tumeurs ou des agents infectieux.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)