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1. (WO2017064488) DOPAMINE D3 RECEPTOR ANTAGONISTS HAVING A MORPHOLINE MOIETY

Pub. No.:    WO/2017/064488    International Application No.:    PCT/GB2016/053169
Publication Date: Fri Apr 21 01:59:59 CEST 2017 International Filing Date: Fri Oct 14 01:59:59 CEST 2016
IPC: C07D 413/14
C07D 413/12
C07D 417/14
A61K 31/5377
A61P 25/18
A61P 25/36
Applicants: INDIVIOR UK LIMITED
Inventors: CREMONESI, Susanna
MICHELI, Fabrizio
SEMERARO, Teresa
TARSI, Luca
Title: DOPAMINE D3 RECEPTOR ANTAGONISTS HAVING A MORPHOLINE MOIETY
Abstract:
The disclosure provides compounds of formula (I) or pharmaceutically acceptable salts thereof: The disclosure also provides processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them, and their use as modulators of dopamine D3 receptors, such as treating substance abuse or psychiatric diseases.