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1. (WO2017064277) NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/064277 International Application No.: PCT/EP2016/074760
Publication Date: 20.04.2017 International Filing Date: 14.10.2016
IPC:
C07D 417/12 (2006.01) ,A61K 31/428 (2006.01) ,C07D 275/06 (2006.01) ,A61P 35/00 (2006.01)
Applicants: INVENTIVA[FR/FR]; 50 rue de Dijon 21121 Daix, FR
Inventors: BARTH, Martine; FR
CONTAL, Sylvie; FR
MONTALBETTI, Christian; FR
SPITZER, Luc; FR
Agent: NEVANT, Marc; FR
HUBERT, Philippe; FR
HART-DAVIS, Jason; FR
LE ROUX, Martine; FR
MARRO, Nicolas; FR
MENA, Sandra; FR
MENDELSOHN, Isabelle; FR
CHANTRAINE, Sylvie; FR
Priority Data:
15306651.915.10.2015EP
Title (EN) NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA
(FR) NOUVEAUX COMPOSÉS INHIBITEURS DE L'INTERACTION YAP/TAZ-TEAD ET LEUR UTILISATION DANS LE TRAITEMENT DU MÉSOTHÉLIOME MALIN
Abstract: front page image
(EN) The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined in the description. The compounds of formula (I) are inhibitors of the YAP/TAZ-TEAD interaction.
(FR) L'invention concerne des composés de formule (I), R1, R2, R3, R4, R5 et R6 étant tels que définis dans les revendications. Les composés de la formule (I) sont des inhibiteurs de l’interaction YAP/TAZ-TEAD.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)