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1. (WO2017064198) HIGH AVIDITY HPV T-CELL RECEPTORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/064198    International Application No.:    PCT/EP2016/074612
Publication Date: 20.04.2017 International Filing Date: 13.10.2016
IPC:
A61K 39/12 (2006.01), C07K 14/725 (2006.01), C07K 14/005 (2006.01), C12N 5/0783 (2010.01), C07K 16/08 (2006.01), A61K 39/00 (2006.01)
Applicants: MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT [DE/DE]; Robert-Rössle-Straße 10 13125 Berlin (DE)
Inventors: BLANKENSTEIN, Thomas; (DE).
WILLIMSKY, Gerald; (DE)
Agent: BOEHMERT & BOEHMERT; Jan B. KRAUSS Pettenkoferstrasse 20 - 22 80336 Munich (DE)
Priority Data:
15190230.1 16.10.2015 EP
Title (EN) HIGH AVIDITY HPV T-CELL RECEPTORS
(FR) RÉCEPTEURS DE LYMPHOCYTES T VPH À HAUTE AVIDITÉ
Abstract: front page image
(EN)The present disclosure provides T cell receptor (TCR) based molecules which are selective and specific for HPV 16/18 proteins E5, E6 and E7. The TCR are of use for the diagnosis, treatment and prevention of HPV infection, as well as for the diagnosis, treatment and prevention of HPV infection.
(FR)La présente invention concerne des molécules à base de récepteurs de lymphocytes T (TCR) qui sont sélectives et spécifiques pour les protéines E5, E6 et E7 VPH 16/18. Les TCR sont utilisés pour le diagnostic, le traitement et la prévention d'infection par VPH, ainsi que pour le diagnostic, le traitement et la prévention d'infection par VPH.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)