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1. (WO2017062871) CROSSLINKED PARTICLES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/062871 International Application No.: PCT/US2016/056135
Publication Date: 13.04.2017 International Filing Date: 07.10.2016
IPC:
C08J 9/16 (2006.01) ,C08J 9/22 (2006.01)
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
J
WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H142
9
Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
16
Making expandable particles
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
J
WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H142
9
Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
22
After-treatment of expandable particles; Forming foamed products
Applicants: LE DÉVÉDEC, Frantz[CA/CA]; US
ALLEN, Christine Jane[CA/CA]; US
STEVENS, David Michael[US/US]; US
RAGER-AGUIAR, Dean James[US/US]; US
RUCKH, Timothy Tordella[US/US]; US
ELMQUIST, Carl Eric[US/US]; US
Inventors: LE DÉVÉDEC, Frantz; US
ALLEN, Christine Jane; US
STEVENS, David Michael; US
RAGER-AGUIAR, Dean James; US
RUCKH, Timothy Tordella; US
ELMQUIST, Carl Eric; US
Agent: LEISEY, Justin J.; US
WESPE, Daniel A.; US
FARMER, Dean; US
BLINKA, Thomas A.; US
Priority Data:
62/239,75809.10.2015US
62/281,63121.01.2016US
62/313,01324.03.2016US
Title (EN) CROSSLINKED PARTICLES
(FR) PARTICULES RÉTICULÉES
Abstract:
(EN) Disclosed are crosslinked particles (e.g., microparticles) that are capable of storing and releasing drugs. The particles can be macroparticles, microparticles, or nanoparticles and can be composed of polyester backbones. The particles can be loaded with a drug. The particles can degrade in vivo to release the drug. The particles can be prepared by crosslinking functionalized polyester backbones and loaded with a given drug. The particles of the present disclosure can be injected with a syringe. In some embodiments, the particles of the present disclosure are administered in connection with a surgery and release the drug after the site of the surgery for a period of 1-6 months.
(FR) L'invention concerne des particules (par exemple des microparticules) réticulées qui sont capables de stocker et de libérer des médicaments. Les particules peuvent être des macroparticules, des microparticules ou des nanoparticules et peuvent être composées de squelettes polyester. Les particules peuvent être chargées avec un médicament. Les particules peuvent se dégrader in vivo pour libérer le médicament. Les particules peuvent être préparées par réticulation de squelettes polyester fonctionnalisés et chargées avec un médicament donné. Les particules de la présente invention peuvent être injectées avec une seringue. Dans certains modes de réalisation, les particules de la présente invention sont administrées en association avec une intervention chirurgicale et libèrent le médicament après le site de l'intervention chirurgicale pendant une période de 1 à 6 mois.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)