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1. (WO2017062688) WNT SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/062688    International Application No.:    PCT/US2016/055851
Publication Date: 13.04.2017 International Filing Date: 06.10.2016
IPC:
A61K 31/4725 (2006.01), A61K 31/444 (2006.01), A61P 43/00 (2006.01)
Applicants: ZHANG, Xiaohu [US/CN]; (CN) (US only).
SUZHOU YUNXUAN YIYAO KEJI YOUXIAN GONGSI [CN/CN]; Suzhou Industrial Park Biobay Campus 218 Xinghu street Building A1 North 2nd Floor, Room E36 Suzhou, Jiangsu 215123 (CN)
Inventors: ZHANG, Xiaohu; (CN)
Agent: TIAN, Feng; (US)
Priority Data:
201510645986.2 08.10.2015 CN
201610195733.4 31.03.2016 CN
201610195731.5 31.03.2016 CN
201610670828.7 16.08.2016 CN
201610850360.X 26.09.2016 CN
201610850358.2 26.09.2016 CN
201610850357.8 26.09.2016 CN
Title (EN) WNT SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF
(FR) INHIBITEURS DE LA VOIE DE SIGNALISATION WNT ET LEURS APPLICATIONS THÉRAPEUTIQUES
Abstract: front page image
(EN)Inhibitors of Wnt signaling pathway with structures of Formula I are disclosed, together with their pharmaceutical salts. Applications of compounds of Formula I in inhibiting or modulating the Wnt signaling pathway are also disclosed. Compounds of Formula I can treat disorders caused by aberrant activation of the Wnt signaling pathway.
(FR)La présente invention concerne des inhibiteurs de la voie de signalisation Wnt présentant des structures de formule I, conjointement avec leurs sels pharmaceutiques. L'invention concerne également des applications des composés de formule I dans l'inhibition ou la modulation de la voie de signalisation Wnt. Les composés de formule I peuvent traiter des troubles provoqués par une activation aberrante de la voie de signalisation Wnt.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)