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1. (WO2017062468) PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/062468    International Application No.:    PCT/US2016/055521
Publication Date: 13.04.2017 International Filing Date: 05.10.2016
IPC:
C07D 233/64 (2006.01), C07D 401/04 (2006.01), C07D 405/10 (2006.01), A61K 31/4174 (2006.01), A61K 31/4439 (2006.01), A61P 21/00 (2006.01)
Applicants: MITOBRIDGE, INC. [US/US]; 1030 Massachusetts Avenue, Suite 200 Cambridge, MA 02138 (US).
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES [US/US]; 10010 N. Torrey Pines Road La Jolla, CA 92037 (US)
Inventors: DOWNES, Michael; (US).
EVANS, Ronald, M.; (US).
KLUGE, Arthur; (US).
LAGU, Bharat; (US).
MIURA, Masanori; (JP).
PANIGRAHI, Sunil, Kumar; (IN).
PATANE, Michael; (US).
SAMAJDAR, Susanta; (IN).
SENAIAR, Ramesh; (IN).
TAKAHASHI, Taisuke; (JP)
Agent: DAVIS, Steven, G.; (US).
ACETO, Donato; (US).
BAI, Mei; (US).
BELT, Erik, P.; (US).
BARBIC, Andrej; (US)
Priority Data:
62/352,348 20.06.2016 US
62/238,629 07.10.2015 US
62/243,263 19.10.2015 US
Title (EN) PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
(FR) AGONISTES DE PPAR, COMPOSÉS, COMPOSITIONS PHARMACEUTIQUES ET MÉTHODES D'UTILISATION DE CEUX-CI
Abstract: front page image
(EN)Provided herein are compounds I, II or III and compositions useful in increasing PPAR8 activity. The compounds and compositions provided herein are useful for the treatment of PPAR8 related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).
(FR)L'invention concerne des composés et des compositions utiles pour renforcer l'activité de PPAR8. Ces composés et ces compositions sont utiles pour le traitement de maladies associées à PPAR8 (par ex., des maladies musculaires, une maladie vasculaire, une maladie démyélinisante et des maladies métaboliques).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)