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1. (WO2017061784) CELLULAR IMMUNOTHERAPEUTIC AGENT COMPOSITION FOR PREVENTING OR TREATING KOREAN INTRACTABLE MULTIPLE MYELOMA, CONTAINING CANCER-TESTIS ANTIGEN, AND PREPARATION METHOD THEREFOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/061784    International Application No.:    PCT/KR2016/011178
Publication Date: 13.04.2017 International Filing Date: 06.10.2016
IPC:
A61K 38/16 (2006.01), C12N 5/09 (2010.01), C12N 5/0784 (2010.01), C12Q 1/68 (2006.01)
Applicants: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY [KR/KR]; 77, Yongbong-ro, Buk-gu, Gwangju 61186 (KR).
VAXCELL-BIO INC. [KR/KR]; 12-55, Sandan-gil, Hwasun-eup, Hwasun-gun Jeollanam-do 58141 (KE)
Inventors: LEE, Je-Jung; (KR).
CHOI, Nu-Ri; (KR).
LEE, Hyun-ju; (KR).
Jung, Sung-Hoon; (KR)
Agent: PLUS INTERNATIONAL IP LAW FIRM; 10F, 809, Hanbat-daero Seo-gu Daejeon 35209 (KR)
Priority Data:
10-2015-0140390 06.10.2015 KR
Title (EN) CELLULAR IMMUNOTHERAPEUTIC AGENT COMPOSITION FOR PREVENTING OR TREATING KOREAN INTRACTABLE MULTIPLE MYELOMA, CONTAINING CANCER-TESTIS ANTIGEN, AND PREPARATION METHOD THEREFOR
(FR) COMPOSITION D’AGENT IMMUNOTHÉRAPEUTIQUE CELLULAIRE POUR LA PRÉVENTION OU LE TRAITEMENT D’UN MYÉLOME MULTIPLE CORÉEN RÉFRACTAIRE, CONTENANT UN ANTIGÈNE DE CANCER DES TESTICULES, ET SON PROCÉDÉ DE PRÉPARATION
(KO) 암-고환 항원을 포함하는 한국 난치성 다발골수종 예방 또는 치료용 세포 면역치료제 조성물 및 그 제조방법
Abstract: front page image
(EN)The present invention relates to a composition for treating or preventing, by cancer immunotherapy, Korean intractable multiple myeloma, containing a cancer-testis antigen. It is expected that a cellular immunotherapeutic agent composition for preventing or treating multiple myeloma, containing, as active ingredients, dendritic cells, having an antigen loaded thereon, and cancer-testis antigen-specific cytotoxic τ lymphocytes derived therefrom, is used so as to induce a strong tumor-specific cytotoxic immune response in cancer immunotherapy and, simultaneously, be useful as a cancer treatment vaccine, which is safe and has no side effects.
(FR)La présente invention concerne une composition pour le traitement ou la prévention, par immunothérapie anticancéreuse, du myélome multiple coréen réfractaire, contenant un antigène du cancer des testicules. Il est attendu qu’une composition d’agent immunothérapeutique cellulaire pour la prévention ou le traitement du myélome multiple, contenant, en tant que substances actives, des cellules dendritiques, comportant un antigène chargé sur celles-ci, et des lymphocytes τ cytotoxiques spécifiques pour l’antigène du cancer des testicules, soit utilisée pour induire une réponse immunitaire cytotoxique spécifique à une tumeur forte dans l’immunothérapie anticancéreuse et, simultanément, être utile en tant que vaccin de traitement anticancéreux, qui est sûr et n’a pas d’effets secondaires.
(KO)본 발명은 암-고환 항원을 포함하는 한국 난치성 다발골수종 암 면역치료 또는 예방용 조성물에 관한 것으로, 상기 항원을 탑재한 수지상세포 및 이로부터 유도되는 암-고환 항원 특이적 세포독성 τ 림프구세포를 유효성분으로 포함하는 다발골수종 예방또는 치료용 세포 면역치료제 조성물을 이용함으로써 암 면역 치료에 있어 강력한 종양 특이적 세포독성 면역 반응을 유도하는 동시에 안전하고 부작용이 없는 암 치료용 백신으로 유용하게 활용할 수 있을 것으로 기대된다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)