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1. (WO2017061780) COMPOSITION COMPRISING LONG-ACTING ERYTHROPOIETIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/061780    International Application No.:    PCT/KR2016/011169
Publication Date: 13.04.2017 International Filing Date: 06.10.2016
IPC:
C07K 14/505 (2006.01), C07K 1/18 (2006.01), C07K 1/34 (2006.01)
Applicants: GREEN CROSS CORPORATION [KR/KR]; (Bojeong-dong) 107, Ihyeon-ro 30beon-gil, Giheung-gu, Yongin-Si, Gyeonggi-do 16924 (KR).
GENEXINE, INC. [KR/KR]; (Sampyeong-dong) B-401, 700, Daewangpangyo-ro, Bundang-gu, Seongnam-si, Gyeonggi-do 13488 (KR)
Inventors: KIM, Min Woo; (KR).
CHUNG, Yo Kyung; (KR).
HAN, Seung Ryel; (KR).
SUNG, Young Chul; (KR).
YANG, Se Hwan; (KR).
WOO, Jung Won; (KR).
YANG, Sang In; (KR)
Agent: DOOHO IP LAW FIRM; (Seocho-dong, Daehyun Blue Tower) 7th Floor, 1, Gangnam-daero 51-gil, Seocho-gu, Seoul 06628 (KR)
Priority Data:
10-2015-0140753 07.10.2015 KR
Title (EN) COMPOSITION COMPRISING LONG-ACTING ERYTHROPOIETIN
(FR) COMPOSITION COMPRENANT DE L'ÉRYTHROPOÏÉTINE À LONGUE DURÉE D'ACTION
Abstract: front page image
(EN)The present invention provides a composition containing long-acting erythropoietin, and a method for preparation thereof. More particularly, there is provided an EPO-Fc fusion protein composition with excellent bio-sustainability and high purity, wherein sialic acid content of EPO-Fc is 17 mol/mol or more, and host cell-derived protein (HCP) impurity is included in an amount of 100 ng/mg or less.
(FR)La présente invention concerne une composition contenant de l'érythropoïétine à longue durée d'action et un procédé de préparation de celle-ci. Plus particulièrement, l'invention concerne une composition de protéine de fusion EPO-Fc dotée d'une excellente bio-durabilité et d'une grande pureté, la teneur en acide sialique de l'EPO-Fc étant de 17 mol/mol ou plus, et une impureté de protéine dérivée de la cellule hôte (HCP) étant incluse en quantité de 100 ng/mg ou moins.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)