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1. (WO2017061150) O/W TYPE EMULSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/061150    International Application No.:    PCT/JP2016/069358
Publication Date: 13.04.2017 International Filing Date: 29.06.2016
IPC:
A61K 47/20 (2006.01), A61K 31/37 (2006.01), A61K 31/573 (2006.01), A61K 45/00 (2006.01), A61K 47/22 (2006.01), A61K 47/24 (2006.01), A61K 47/28 (2006.01), A61K 47/34 (2017.01), A61K 9/107 (2006.01), A61P 29/00 (2006.01), A61P 3/06 (2006.01), A61P 31/00 (2006.01), A61P 31/04 (2006.01), A61P 31/10 (2006.01), A61P 35/00 (2006.01), A61P 37/06 (2006.01)
Applicants: NOF CORPORATION [JP/JP]; 20-3, Ebisu 4-chome, Shibuya-ku, Tokyo 1506019 (JP).
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY [JP/JP]; Kita 8-jyo Nishi 5-chome, Kita-ku, Sapporo-shi, Hokkaido 0600808 (JP)
Inventors: TANGE, Kota; (JP).
NAKAI, Yuta; (JP).
AKITA, Hidetaka; (JP).
TANAKA, Hiroki; (JP).
WATANABE, Ayaka; (JP).
MIURA, Naoya; (JP).
HARASHIMA, Hideyoshi; (JP)
Agent: TAKASHIMA, Hajime; (JP)
Priority Data:
2015-200148 08.10.2015 JP
Title (EN) O/W TYPE EMULSION
(FR) ÉMULSION DE TYPE H/E
(JA) O/W型エマルション
Abstract: front page image
(EN)The present invention provides an O/W type emulsion which has a volume median diameter of 100 nm or less and which contains a compound represented by formula (1) (in the formula, Xa and Xb are each independently X1, X2 or a 1,4-piperazinediyl group, s is 1 or 2, R4 denotes an alkyl group having 1-6 carbon atoms, na and nb are each independently 0 or 1, R1a, R1b, R2a and R2b each independently denote an alkylene group having 1-6 carbon atoms, Ya and Yb each independently denote an ester bond or the like, and R3a and R3b each independently denote a fat-soluble vitamin residue or the like).
(FR)La présente invention concerne une émulsion de type H/E qui a un diamètre volumétrique médian inférieur ou égal à 100 nm et qui contient un composé représenté par la formule (1) (dans la formule, Xa et Xb sont chacun indépendamment X1, X2 ou un groupe 1,4-pipérazinédiyle, s est 1 ou 2, R4 représente un groupe alkyle ayant 1 à 6 atomes de carbone, na et nb sont chacun indépendamment 0 ou 1, R1a, R1b, R2a et R2b représentent chacun indépendamment un groupe alkylène ayant 1 à 6 atomes de carbone, Ya et Yb représentent chacun indépendamment une liaison ester ou similaire et R3a et R3b représentent chacun indépendamment un résidu de vitamine liposoluble ou similaire).
(JA)本発明は、式(1)(式中、X及びXは独立して、X、X又は1,4-ピペラジンジイル基であり;sは1又は2であり、Rは炭素数1~6のアルキル基を表し、n及びnは独立して、0又は1であり、R1a、R1b、R2a、R2bは独立して、炭素数1~6のアルキレン基を表し、Y及びYは独立して、エステル結合等を表し、R3a及びR3bは独立して、脂溶性ビタミン残基等を表す)で示される化合物を含む、体積メディアン径が100nm以下であるO/W型エマルションを提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)