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Machine translation
1. (WO2017060912) METHODS AND KITS FOR PREDICTION AND DIAGNOSIS OF HUMAN CYTOMEGALOVIRUS CONGENITAL (hCMV) TRANSMISSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/060912    International Application No.:    PCT/IL2016/051097
Publication Date: 13.04.2017 International Filing Date: 09.10.2016
IPC:
C12Q 1/68 (2006.01), G01N 33/50 (2006.01), G06F 19/20 (2011.01)
Applicants: GENEFRON LTD. [IL/IL]; POB 120 9083600 Har Adar (IL)
Inventors: SMITH, Yoav; (IL)
Agent: KESTEN, Dov; (IL)
Priority Data:
62/239,609 09.10.2015 US
62/353,624 23.06.2016 US
Title (EN) METHODS AND KITS FOR PREDICTION AND DIAGNOSIS OF HUMAN CYTOMEGALOVIRUS CONGENITAL (hCMV) TRANSMISSION
(FR) MÉTHODES ET TROUSSES DE PRÉDICTION ET DE DIAGNOSTIC D'UNE TRANSMISSION CONGÉNITALE DU CYTOMÉGALOVIRUS HUMAIN (HCMV)
Abstract: front page image
(EN)The present invention relates to methods and kits for the prediction and diagnosis of intrauterine-transmission of viral pathogens, specifically, hCMV in a mammalian subject, by calculating the ability of a subject to prevent transmission of said hCMV based on determining the expression of ISG15, IFIT3 and USP18 genes and optionally of EIF2AK2, HERC5, RSAD2 and MX1 genes in a sample of said subject.
(FR)La présente invention concerne des méthodes et des trousses de prédiction et de diagnostic de la transmission intra-utérine de pathogènes viraux, spécifiquement, du hCMV chez un sujet mammifère, en calculant la capacité d'un sujet à prévenir la transmission dudit hCMV sur la base de la détermination de l'expression des gènes ISG15, IFIT3 et USP18 et éventuellement des gènes EIF2AK2, HERC5, RSAD2 et MX1 dans un prélèvement provenant dudit sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)