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Machine translation
1. (WO2017060854) BIARYL PYRAZOLES AS NRF2 REGULATORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/060854    International Application No.:    PCT/IB2016/055996
Publication Date: 13.04.2017 International Filing Date: 06.10.2016
IPC:
C07D 401/14 (2006.01), C07D 401/12 (2006.01), C07D 401/10 (2006.01), C07D 401/06 (2006.01), C07D 401/04 (2006.01), A61K 31/41 (2006.01), A61K 31/4196 (2006.01), A61K 31/445 (2006.01)
Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED [GB/GB]; 980 Great West Road Brentford Middlesex TW89GS (GB).
ASTEX THERAPEUTICS LIMITED [GB/GB]; 436 Cambridge Science Park Milton Road Cambridge Cambridgeshire (GB)
Inventors: CALLAHAN, James Francis; (US).
KERNS, Jeffrey K.; (US).
LI, Peng; (US).
LI, Tindy; (US).
MCCLELAND, Brent W.; (US).
NIE, Hong; (US).
PERO, Joseph E.; (US).
DAVIES, Thomas Glanmor; (GB).
GRAZIA CARR, Maria; (GB).
GRIFFITHS-JONES, Charlotte Mary; (GB).
HEIGHTMAN, Thomas Daniel; (GB).
NORTON, David; (GB).
VERDONK, Marinus Leendert; (GB).
WOOLFORD, Alison Jo-Anne; (GB).
WILLEMS, Hendrika Maria Gerarda; (GB)
Priority Data:
62/237,655 06.10.2015 US
Title (EN) BIARYL PYRAZOLES AS NRF2 REGULATORS
(FR) BIARYL PYRAZOLES UTILISÉS COMME RÉGULATEURS DE NRF2
Abstract: front page image
(EN)The present invention relates to biaryl pyrazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.
(FR)La présente invention concerne des composés biaryl pyrazoles, des procédés de production de ceux-ci, des compositions pharmaceutiques les contenant et leur utilisation comme régulateurs de NRF2.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)