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1. (WO2017059158) TRANSGLUTAMINASE VARIANTS FOR CONJUGATING ANTIBODIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/059158    International Application No.:    PCT/US2016/054585
Publication Date: 06.04.2017 International Filing Date: 30.09.2016
IPC:
A61K 47/68 (2017.01), C12N 9/10 (2006.01)
Applicants: BRISTOL-MYERS SQUIBB COMPANY [US/US]; Route 206 and Province Line Road Princeton, New Jersey 08543 (US)
Inventors: RAO-NAIK, Chetana; (US).
SARMA, Ganapathy N.; (US).
NAYEEM, Akbar; (US)
Agent: CHAO, Yuan; (US).
BELLOMY, Gregory R.; (US).
BERGEN, Briana C.; (US).
CLAUSS, Isabelle M.; (US).
D'AMICO, Stephen C.; (US).
DELAUNEY, Ashton J.; (US).
EPPERSON, James; (US).
FARQUHARSON-TORRES, Serena; (US).
FRANK, Eve; (US).
GOLIAN, Paul D.; (US).
GREENBLATT, Gary D.; (US).
GUO, Z. Angela; (US).
HADAD, Henry; (US).
HAI, Bing; (US).
JACOBSEN, Barry H.; (US).
KORSEN, Elliott; (US).
LIU, Hong; (US).
LU, Yong; (US).
MINGO, Pamela A.; (US).
PARLET, Nickki L.; (US).
SUN, Jing G.; (US).
VANATTEN, Mary K.; (US).
VOLLES, Warren K.; (US).
WALSH, Brian J.; (US)
Priority Data:
62/236,274 02.10.2015 US
Title (EN) TRANSGLUTAMINASE VARIANTS FOR CONJUGATING ANTIBODIES
(FR) VARIANTS DE TRANSGLUTAMINASE POUR CONJUGUER DES ANTICORPS
Abstract: front page image
(EN)Transglutaminase variants capable of conjugating an antibody that is not conjugated by wild-type transglutaminase from Streptomyces mobaraensis.
(FR)L'invention concerne des variants de transglutaminase pouvant conjuguer un anticorps qui n'est pas conjugué par la transglutaminase de type sauvage à partir de Streptomyces mobaraensis.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)