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1. (WO2017059139) TETRAHYDRO-1H-PYRIDO[3,4-b]INDOLE ANTI-ESTROGENIC DRUGS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/059139    International Application No.:    PCT/US2016/054549
Publication Date: 06.04.2017 International Filing Date: 29.09.2016
IPC:
A61K 31/437 (2006.01), A61K 31/506 (2006.01), A61K 31/4545 (2006.01), C07D 471/02 (2006.01), C07D 471/04 (2006.01)
Applicants: OLEMA PHARMACEUTICALS, INC. [US/US]; 665 3rd Street, #250 San Francisco, CA 94107 (US)
Inventors: MYLES, David, C.; (US).
KUSHNER, Peter, J.; (US).
HARMON, Cyrus, L.; (US)
Agent: SHINALL, Michael, A.; (US).
AUGST, Alexander D.; (US).
BUTEAU, Kristen C.; (US).
CAHILL, John J.; (US).
HAULBROOK, William R.; (US).
JARRELL, Brenda Herschbach; (US).
LI, Xiaodong; (US).
LYON, Charles E.; (US).
MEDINA, Rolando; (US).
MONROE, Margo R.; (US).
NGUYEN, Suzanne P.; (US).
NIHAN, Danielle M.; (US).
PACE, Nicholas J.; (US).
PELLIGRINO, Jeffrey S.; (US).
PYSHER, Paul A.; (US).
REARICK, John P.; (US).
REESE, Brian E.; (US).
ROHLFS, Elizabeth M.; (US).
SAHR, Robert N.; (US).
SCHONEWALD, Stephanie L.; (US).
SHAIKH, Nishat A.; (US).
SMITH, Maria C.; (US).
SUH, Su Kyung; (US).
VETTER, Michael L.; (US).
VRABLIK, Tracy L.; (US).
WANG, Gang; (US)
Priority Data:
62/235,900 01.10.2015 US
Title (EN) TETRAHYDRO-1H-PYRIDO[3,4-b]INDOLE ANTI-ESTROGENIC DRUGS
(FR) MÉDICAMENTS ANTI-ŒSTROGÉNIQUES DE TYPE TÉTRAHYDRO-1H-PYRIDO[3,4-B]INDOLE
Abstract: front page image
(EN)The present disclosure provides tetrahydro-1H-pyrido[3,4-b]indole compounds or a pharmaceutically acceptable salt, solvate, hydrate, prodrug, stereoisomer, tautomer, rotamer, N-oxide and/or substituted derivative or, optionally in a pharmaceutical composition, for the modulation of disorders mediated by estrogen, or other disorders as more fully described herein.
(FR)La présente divulgation concerne des composés de tétrahydro-1H-pyrido[3,4-b]indole ou un sel pharmaceutiquement acceptable, un solvate, un hydrate, un promédicament, un stéréoisomère, un tautomère, un rotamère, un N-oxyde et/ou un dérivé substitué de ceux-ci ou, éventuellement, dans une composition pharmaceutique, pour la modulation des troubles médiés par les œstrogènes, ou d'autres troubles tels que décrits plus en détails dans l'exposé.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)