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1. (WO2017059095) ANTI-TIGIT ANTIGEN-BINDING PROTEINS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/059095    International Application No.:    PCT/US2016/054484
Publication Date: 06.04.2017 International Filing Date: 29.09.2016
IPC:
C07K 16/28 (2006.01), A61K 39/00 (2006.01)
Applicants: POTENZA THERAPEUTICS, INC. [US/US]; 1030 Massachusetts Avenue Suite 210 Cambridge, Massachusetts 02138 (US)
Inventors: HICKLIN, Daniel; (US).
WINSTON, William; (US).
SEIDEL-DUGAN, Cynthia; (US).
NIELSON, Nels P.; (US)
Agent: KABLER, Kevin E.; (US).
STOLE, Einar; (US).
REISTER, Andrea G.; (US)
Priority Data:
62/235,990 01.10.2015 US
Title (EN) ANTI-TIGIT ANTIGEN-BINDING PROTEINS AND METHODS OF USE THEREOF
(FR) PROTÉINES DE LIAISON À UN ANTIGÈNE ANTI-TIGIT ET LEURS MÉTHODES D'UTILISATION
Abstract: front page image
(EN)Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
(FR)La présente invention concerne des protéines de liaison à un antigène (ABP) qui se lient sélectivement à TIGIT et ses isoformes et homologues, ainsi que des compositions comprenant lesdits anticorps. L'invention concerne également des méthodes d'utilisation desdites ABP, notamment des méthodes diagnostiques et thérapeutiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)