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1. (WO2017058174) COMPOSITION FOR MAINTAINING LOCTOBACILLUS DOMINANCE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/058174    International Application No.:    PCT/US2015/052951
Publication Date: 06.04.2017 International Filing Date: 29.09.2015
IPC:
A61K 31/7016 (2006.01), A61K 31/719 (2006.01), A61K 31/702 (2006.01), A61K 31/194 (2006.01)
Applicants: KIMBERLY-CLARK WORLDWIDE, INC. [US/US]; 2300 Winchester Road Neenah, Wisconsin 54956 (US)
Inventors: LI, Jingru; (US).
PEED, Lindsay, Adrienne; (US).
JOYNER, Cheryce, Francina; (US).
VONGSA, Rebecca, Ann; (US).
KOENIG, David, William; (US).
BARTELL, Ryan, Daniel; (US)
Agent: SULLIVAN, Michael J.; (US)
Priority Data:
Title (EN) COMPOSITION FOR MAINTAINING LOCTOBACILLUS DOMINANCE
(FR) COMPOSITION POUR LE MAINTIEN DE LA DOMINANCE DE LACTOBACILLUS
Abstract: front page image
(EN)The present invention provides compositions and formulations capable of maintaining or promoting the growth of certain strains of Lactobacilli spp. The compositions and formulations generally comprise only a single therapeutic agent selected from the group consisting of isomaltulose, maltitol, pullulan, maltotriose, 2-deoxy-D-ribose, 1-kestose and erlose. The single therapeutic agent is the sole source of carbon for bacterium when administered to a user. Despite comprising only a single therapeutic agent the compositions have been shown to promote the growth and maintenance of beneficial lactobacilli and to effectively inhibit the growth of pathogens associated with urogenital infections. As such administration of the compositions maintain a healthy microflora balance in the urogenital area.
(FR)La présente invention concerne des compositions et des formulations aptes à maintenir ou faciliter la croissance de certaines souches de Lactobacilli spp. Les compositions et formulations comprennent généralement un seul agent thérapeutique choisi dans le groupe constitué des éléments suivants : isomaltulose, maltitol, pullulane, maltotriose, 2-désoxy-D-ribose, 1-kestose et erlose. L'agent thérapeutique unique est la seule source de carbone pour bactérie lorsqu'il est administré à un utilisateur. Bien qu'elles ne comportent qu'un seul agent thérapeutique, les compositions selon l'invention se sont révélées favoriser la croissance et le maintien de lactobacilles bénéfiques et inhiber efficacement la croissance d'agents pathogènes associés à des infections urogénitales. Ainsi, l'administration des compositions maintient un équilibre sain de la microflore dans la zone urogénitale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)